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ChemicalBook >> CAS DataBase List >> SGC707

SGC707

SGC707 price.
  • $32 - $1829
  • Product name: SGC707
  • CAS: 1687736-54-4
  • MF: C16H18N4O2
  • MW: 298.34
  • EINECS:
  • MDL Number:MFCD28411624
  • Synonyms:SGC707;N-6-Isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea;SGC 707;SGC707;CS-2192;Urea, N-6-isoquinolinyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]-;S C 707;SGC707, 10 mM in DMSO
52 prices
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Brand
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Tocris
  • TRC
Package
  • 1mg
  • 50.00mg
  • 100.00mg
  • 250mg
  • 10mM*1mLinDMSO
  • 500mg
  • 50
  • 250.00mg
  • 5MG
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
  • 25MG
  • 50mg
  • 1G
  • 10mM*1mLinDMSO(Solution)
  • 100MG
  • ManufacturerACHEMBLOCK
  • Product numberQ65800
  • Product description1-(isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98%
  • Packaging5MG
  • Price$65
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65800
  • Product description1-(isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98%
  • Packaging25MG
  • Price$145
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65800
  • Product description1-(isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98%
  • Packaging100MG
  • Price$425
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65800
  • Product description1-(isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98%
  • Packaging1G
  • Price$1330
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number4586EB
  • Product description1-Isoquinolin-6-Yl-3-[2-Oxo-2-(Pyrrolidin-1-Yl)ethyl]urea
  • Packaging100mg
  • Price$1064
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6048
  • Product descriptionSGC707
  • Packaging50mg
  • Price$176
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6048
  • Product descriptionSGC707
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6048
  • Product descriptionSGC707
  • Packaging10mg
  • Price$55
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-19715
  • Product descriptionSGC707 99.99%
  • Packaging10mg
  • Price$69
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19715
  • Product descriptionSGC707 99.99%
  • Packaging5mg
  • Price$44
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19715
  • Product descriptionSGC707 99.99%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$48
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19715
  • Product descriptionSGC707 99.99%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$48
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19715
  • Product descriptionSGC707 99.99%
  • Packaging25mg
  • Price$143
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19715
  • Product descriptionSGC707 99.99%
  • Packaging50mg
  • Price$236
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19715
  • Product descriptionSGC707 99.99%
  • Packaging100mg
  • Price$471
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19715
  • Product descriptionSGC707 99.99%
  • Packaging500mg
  • Price$1829
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK Q65800 1-(isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98% 5MG $65 2026-05-27 Buy
ACHEMBLOCK Q65800 1-(isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98% 25MG $145 2026-05-27 Buy
ACHEMBLOCK Q65800 1-(isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98% 100MG $425 2026-05-27 Buy
ACHEMBLOCK Q65800 1-(isoquinolin-6-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea 98% 1G $1330 2026-05-27 Buy
AK Scientific 4586EB 1-Isoquinolin-6-Yl-3-[2-Oxo-2-(Pyrrolidin-1-Yl)ethyl]urea 100mg $1064 2021-12-16 Buy
ApexBio Technology B6048 SGC707 50mg $176 2026-05-06 Buy
ApexBio Technology B6048 SGC707 10mg $75 2021-12-16 Buy
ApexBio Technology B6048 SGC707 10mg $55 2026-05-06 Buy
Arctom HY-19715 SGC707 99.99% 10mg $69 2026-05-26 Buy
Arctom HY-19715 SGC707 99.99% 5mg $44 2026-05-26 Buy
Arctom HY-19715 SGC707 99.99% 10mM*1mLinDMSO(Solid+Solvent) $48 2026-05-26 Buy
Arctom HY-19715 SGC707 99.99% 10mM*1mLinDMSO(Solution) $48 2026-05-26 Buy
Arctom HY-19715 SGC707 99.99% 25mg $143 2026-05-26 Buy
Arctom HY-19715 SGC707 99.99% 50mg $236 2026-05-26 Buy
Arctom HY-19715 SGC707 99.99% 100mg $471 2026-05-26 Buy
Arctom HY-19715 SGC707 99.99% 500mg $1829 2026-05-26 Buy

Properties

storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :1S/C16H18N4O2/c21-15(20-7-1-2-8-20)11-18-16(22)19-14-4-3-13-10-17-6-5-12(13)9-14/h3-6,9-10H,1-2,7-8,11H2,(H2,18,19,22)
InChIKey :DMIDPTCQPIJYFE-UHFFFAOYSA-N
SMILES :O=C(NCC(N1CCCC1)=O)NC2=CC3=CC=NC=C3C=C2

Safety Information

Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Protein arginine N-methyltransferase 3 (PRMT3, ) is a predominantly cytoplasmic enzyme that is constitutively expressed. SGC707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. Developed by the Structural Genomics Consortium (SGC), SGC707 avidly binds PRMT3 (Kd = 50 nM by isothermal titration calorimetry) and inhibits the methylation of histones in cells with an IC50 value below 1 μM.

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