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ChemicalBook >> CAS DataBase List >> 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide

3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide price.
  • $80 - $1500
  • Product name: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
  • CAS: 199666-03-0
  • MF: C17H15N3O6S2
  • MW: 421.45
  • EINECS:
  • MDL Number:MFCD11040807
  • Synonyms:Ro 61-8048, >=98%;RO61-80483,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)Benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide RO61-8048;RO 61-8048 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;KMO Inhibitor I, Ro 61-8048 ;3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide;3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide;3,4-diMethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonaMide
21 prices
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  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mg-m
  • ManufacturerAK Scientific
  • Product numberSYN5225
  • Product descriptionRo 61-8048
  • Packaging50mg
  • Price$410
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7334
  • Product descriptionRo 61-8048
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7334
  • Product descriptionRo 61-8048
  • Packaging50mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2139
  • Product descriptionRo 61-8048 99%
  • Packaging10mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2139
  • Product descriptionRo 61-8048 99%
  • Packaging50mg
  • Price$368.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15199
  • Product descriptionRo 61-8048 ≥98%
  • Packaging5mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15199
  • Product descriptionRo 61-8048 ≥98%
  • Packaging10mg
  • Price$112
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15199
  • Product descriptionRo 61-8048 ≥98%
  • Packaging25mg
  • Price$258
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15199
  • Product descriptionRo 61-8048 ≥98%
  • Packaging50mg
  • Price$356
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM190466
  • Product description3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-benzenesulfonamide 98%
  • Packaging100mg
  • Price$229
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002769
  • Product descriptionRo 61-8048 98+%
  • Packaging100mg
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002769
  • Product descriptionRo 61-8048 98+%
  • Packaging250mg
  • Price$548
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN13615
  • Product descriptionRo 61-8048
  • Packaging25mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN13615
  • Product descriptionRo 61-8048
  • Packaging50mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN13615
  • Product descriptionRo 61-8048
  • Packaging100mg
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7656
  • Product descriptionRo 61-8048 >98%
  • Packaging1g
  • Price$1500
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5225 Ro 61-8048 50mg $410 2021-12-16 Buy
ApexBio Technology B7334 Ro 61-8048 10mg $80 2021-12-16 Buy
ApexBio Technology B7334 Ro 61-8048 50mg $210 2021-12-16 Buy
Axon Medchem Axon2139 Ro 61-8048 99% 10mg $104.5 2021-12-16 Buy
Axon Medchem Axon2139 Ro 61-8048 99% 50mg $368.5 2021-12-16 Buy
Cayman Chemical 15199 Ro 61-8048 ≥98% 5mg $81 2024-03-01 Buy
Cayman Chemical 15199 Ro 61-8048 ≥98% 10mg $112 2024-03-01 Buy
Cayman Chemical 15199 Ro 61-8048 ≥98% 25mg $258 2024-03-01 Buy
Cayman Chemical 15199 Ro 61-8048 ≥98% 50mg $356 2024-03-01 Buy
Chemenu CM190466 3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-benzenesulfonamide 98% 100mg $229 2021-12-16 Buy
Crysdot CD31002769 Ro 61-8048 98+% 100mg $295 2021-12-16 Buy
Crysdot CD31002769 Ro 61-8048 98+% 250mg $548 2021-12-16 Buy
CSNpharm CSN13615 Ro 61-8048 25mg $117 2021-12-16 Buy
CSNpharm CSN13615 Ro 61-8048 50mg $187 2021-12-16 Buy
CSNpharm CSN13615 Ro 61-8048 100mg $298 2021-12-16 Buy
DC Chemicals DC7656 Ro 61-8048 >98% 1g $1500 2021-12-16 Buy

Properties

Melting point :185℃
Boiling point :627.4±65.0 °C(Predicted)
Density :1.471±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
form :Yellow solid
pka :6.29±0.10(Predicted)
color :faint yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The kynurenine pathway mediates the metabolism of L-tryptophan to NAD+ and is particularly important in neurophysiology. Ro 61-8048 is a potent inhibitor of kynurenine 3-hydroxylase (IC50 = 37 nM), preventing the conversion of kynurenine to 3-hydroxy kynurenine. Ro 61-8048 inhibition of kynurenine 3-hydroxylase reduces ischemia-mediated neuronal damage in tissues. Ro 61-8048 can be used in vivo by direct injection.

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