DBeQ
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- $21 - $1802
- Product name: DBeQ
- CAS: 177355-84-9
- MF: C22H20N4
- MW: 340.42
- EINECS:
- MDL Number:MFCD03691820
- Synonyms:DBeQ;2,4-QuinazolinediaMine, N2,N4-bis(phenylMethyl)-;2,4-QuinazolinediaMine, N,N'-bis(phenylMethyl)-;JRF 12;N,N'-Dibenzylquinazoline-2,4-diamine;N2,N4-Dibenzylquinazoline-2,4-diamine;JRF;N,N'-Dibenzylquinazoline-2,4-diamine DBeQ
42 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number2360AH
- Product description2-N,4-N-dibenzylquinazoline-2,4-diamine
- Packaging5mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA391735
- Product descriptionDBeQ 98+%
- Packaging5mg
- Price$21
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA391735
- Product descriptionDBeQ 98+%
- Packaging10mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA391735
- Product descriptionDBeQ 98+%
- Packaging50mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA391735
- Product descriptionDBeQ 98+%
- Packaging100mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA391735
- Product descriptionDBeQ 98+%
- Packaging250mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA391735
- Product descriptionDBeQ 98+%
- Packaging1g
- Price$295
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001272
- Product descriptionN2,N4-BIS(PHENYLMETHYL)-2,4-QUINAZOLINEDIAMINE 95.00%
- Packaging10MG
- Price$245.7
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001272
- Product descriptionN2,N4-BIS(PHENYLMETHYL)-2,4-QUINAZOLINEDIAMINE 95.00%
- Packaging50MG
- Price$1241.63
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8629
- Product descriptionDBeQ
- Packaging10mM(in 1mL DMSO)
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8629
- Product descriptionDBeQ
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8629
- Product descriptionDBeQ
- Packaging50mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1826
- Product descriptionDBeQ 99%
- Packaging50mg
- Price$297
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545855
- Product descriptionDbeQ >98%
- Packaging5mg
- Price$181.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545855
- Product descriptionDbeQ >98%
- Packaging25mg
- Price$489.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181411
- Product descriptionDBeQ >98%
- Packaging100mg
- Price$606.9
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2360AH | 2-N,4-N-dibenzylquinazoline-2,4-diamine | 5mg | $138 | 2021-12-16 | Buy |
| Ambeed | A391735 | DBeQ 98+% | 5mg | $21 | 2021-12-16 | Buy |
| Ambeed | A391735 | DBeQ 98+% | 10mg | $27 | 2021-12-16 | Buy |
| Ambeed | A391735 | DBeQ 98+% | 50mg | $46 | 2021-12-16 | Buy |
| Ambeed | A391735 | DBeQ 98+% | 100mg | $73 | 2021-12-16 | Buy |
| Ambeed | A391735 | DBeQ 98+% | 250mg | $122 | 2021-12-16 | Buy |
| Ambeed | A391735 | DBeQ 98+% | 1g | $295 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001272 | N2,N4-BIS(PHENYLMETHYL)-2,4-QUINAZOLINEDIAMINE 95.00% | 10MG | $245.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001272 | N2,N4-BIS(PHENYLMETHYL)-2,4-QUINAZOLINEDIAMINE 95.00% | 50MG | $1241.63 | 2021-12-16 | Buy |
| ApexBio Technology | A8629 | DBeQ | 10mM(in 1mL DMSO) | $66 | 2021-12-16 | Buy |
| ApexBio Technology | A8629 | DBeQ | 10mg | $90 | 2021-12-16 | Buy |
| ApexBio Technology | A8629 | DBeQ | 50mg | $340 | 2021-12-16 | Buy |
| Axon Medchem | Axon1826 | DBeQ 99% | 50mg | $297 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545855 | DbeQ >98% | 5mg | $181.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545855 | DbeQ >98% | 25mg | $489.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181411 | DBeQ >98% | 100mg | $606.9 | 2021-12-16 | Buy |
Properties
Melting point :149 °C
Boiling point :573.1±52.0 °C(Predicted)
Density :1.259±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
form :powder
pka :7.78±0.30(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :QAIMUUJJAJBPCL-UHFFFAOYSA-N
CAS DataBase Reference :177355-84-9
Boiling point :573.1±52.0 °C(Predicted)
Density :1.259±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
form :powder
pka :7.78±0.30(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :QAIMUUJJAJBPCL-UHFFFAOYSA-N
CAS DataBase Reference :177355-84-9
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
The ATPase p97 is an ubiquitin-selective chaperone known to play a critical role in the degradation of misfolded membrane and secretory proteins and has been linked to various cellular processes that require unfolding and disassembly of protein complexes. DBeQ is a selective, reversible, and ATP-competitive inhibitor of the ATPase p97 (Ki = 3.2 μM; IC50 = 1.5 μM). It does not exhibit activity when tested against a panel 170 protein kinases at concentrations as high as 15 μM. At 10 μM it blocks endoplasmic reticulum-associated degradation, impairing the autophagy pathway and promoting the activation of caspase-3 and -7 in cancer cells.Related product price
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