SWAINSONINE
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- $45 - $1593.9
- Product name: SWAINSONINE
- CAS: 72741-87-8
- MF: C8H15NO3
- MW: 173.21
- EINECS:
- MDL Number:MFCD00017554
- Synonyms:8-indolizinetriol,octahydro-,(1s,2r,8r,8ar)-2 ;(1S,2S,8R,8AR)-TRIHYDROXYINDOLIZIDINE;(1S,2R,8R,8AR)-1,2,8-OCTAHYDROINDOLIZIDINETRIOL;8ALPHA,BETA-INDOLIZIDINE-1,2ALPHA,8BETA-TRIOL;8ALPHA,BETA-INDOLIZIDINE-1ALPHA,2ALPHA,8BETA-TRIOL;8A-BETA-INDOLIZIDINE-1ALPHA,2ALPHA,8BETA-TRIOL;8A,B-INDOLIZIDINE-1,2A,8B-TRIOL;8A,B-OCTAHYDROINDOLIZIDINE-1A,2A,8B-TRIOL
32 prices
Selected condition：
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 0.1mg
- 0.5mg
- 2mg
- 500μg
- 1mg
- 1
- 5mg
- 0.005g
- 10MG
- 25mg
- ManufacturerAHH
- Product numberMT-58882
- Product descriptionSwainsonine 98%
- Packaging0.005g
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2057AH
- Product descriptionSwainsonine
- Packaging1mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004300
- Product descriptionSWAINSONINE 95.00%
- Packaging1MG
- Price$205.8
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004300
- Product descriptionSWAINSONINE 95.00%
- Packaging10MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7316
- Product descriptionSwainsonine
- Packaging1mg
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY077069
- Product descriptionSwainsonine,99% ≥98%
- Packaging1mg
- Price$638.18
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546095
- Product descriptionSwainsonine >98%
- Packaging1mg
- Price$190.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546095
- Product descriptionSwainsonine >98%
- Packaging5mg
- Price$521.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMS10129
- Product descriptionSwainsonine
- Packaging1mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMS10129
- Product descriptionSwainsonine
- Packaging2mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMS10129
- Product descriptionSwainsonine
- Packaging5mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMS10129
- Product descriptionSwainsonine
- Packaging10mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberMS10129
- Product descriptionSwainsonine
- Packaging25mg
- Price$875
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16860
- Product descriptionSwainsonine ≥98%
- Packaging500μg
- Price$55
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16860
- Product descriptionSwainsonine ≥98%
- Packaging1mg
- Price$101
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16860
- Product descriptionSwainsonine ≥98%
- Packaging5mg
- Price$420
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-58882 | Swainsonine 98% | 0.005g | $370 | 2021-12-16 | Buy |
| AK Scientific | 2057AH | Swainsonine | 1mg | $210 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004300 | SWAINSONINE 95.00% | 1MG | $205.8 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004300 | SWAINSONINE 95.00% | 10MG | $1593.9 | 2021-12-16 | Buy |
| ApexBio Technology | B7316 | Swainsonine | 1mg | $113 | 2021-12-16 | Buy |
| Arctom | SY077069 | Swainsonine,99% ≥98% | 1mg | $638.18 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546095 | Swainsonine >98% | 1mg | $190.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546095 | Swainsonine >98% | 5mg | $521.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MS10129 | Swainsonine | 1mg | $70 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MS10129 | Swainsonine | 2mg | $120 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MS10129 | Swainsonine | 5mg | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MS10129 | Swainsonine | 10mg | $390 | 2021-12-16 | Buy |
| Biosynth Carbosynth | MS10129 | Swainsonine | 25mg | $875 | 2021-12-16 | Buy |
| Cayman Chemical | 16860 | Swainsonine ≥98% | 500μg | $55 | 2024-03-01 | Buy |
| Cayman Chemical | 16860 | Swainsonine ≥98% | 1mg | $101 | 2024-03-01 | Buy |
| Cayman Chemical | 16860 | Swainsonine ≥98% | 5mg | $420 | 2024-03-01 | Buy |
Properties
Melting point :148-149°C
Boiling point :353.3±21.0 °C(Predicted)
Density :1.38±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :-20°C
solubility :H2O: soluble1mg/mL
pka :14.01±0.60(Predicted)
form :lyophilized powder
color :white to faint yellow
Water Solubility :Soluble to 50 mM in water
BRN :4175740
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :72741-87-8
Boiling point :353.3±21.0 °C(Predicted)
Density :1.38±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :-20°C
solubility :H2O: soluble1mg/mL
pka :14.01±0.60(Predicted)
form :lyophilized powder
color :white to faint yellow
Water Solubility :Soluble to 50 mM in water
BRN :4175740
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :72741-87-8
Safety Information
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Description
Swainsonine is an indolizidine alkaloid naturally found in certain plants including locoweed that inhibits N-linked glycoside hydrolases, preventing the processing of asparagine-linked glycoproteins. It reversibly inhibits lysosomal α-mannosidase and Golgi α-mannosidase II (IC50 = 0.2 μM). Swainsonine is used to study the role of N-linked glycosylation in cellular processes and has been shown to have antiproliferative and antimetastatic effects of cancer cells in culture and in mice. The inhibition of α-mannosidase activity in lysosomes produces an accumulation of partially-processed oligosaccharides and glycoproteins, giving rise to lysosomal storage disease. Swainsonine toxicity in herbivores results in a condition known as locoism, characterized by hyperactivity, aggression, stiff and clumsy gait, low head carriage, salivation, seizures, and apparent blindness, culminating in increased miscoordination, weakness and death.More related product prices
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