TC 14012
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- $86 - $5262
- Product name: TC 14012
- CAS: 368874-34-4
- MF: C90H140N34O19S2
- MW: 2066.43
- EINECS:
- MDL Number:MFCD19690961
- Synonyms:TC 14012;L-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide;SGDDHDBBOJNZKY-LNDHEDFZSA-N;TC 14012 （TFA ）;TC 14012, Peptidomimetic CXCR4 antagonist
30 prices
Selected condition：
Brand
- aablocks
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Tocris
- Usbiological
Package
- 1
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- Manufactureraablocks
- Product numberAA01E48Y
- Product descriptionL-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide ≥95%
- Packaging1mg
- Price$177
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E48Y
- Product descriptionL-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide ≥95%
- Packaging5mg
- Price$589
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E48Y
- Product descriptionL-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide ≥95%
- Packaging10mg
- Price$824
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E48Y
- Product descriptionL-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide ≥95%
- Packaging50mg
- Price$2884
- Updated2026-05-30
- Buy
- ManufacturerApexBio Technology
- Product numberB7639
- Product descriptionTC 14012
- Packaging10mg
- Price$787
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7639
- Product descriptionTC 14012
- Packaging5mg
- Price$488
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7639
- Product descriptionTC 14012
- Packaging1mg
- Price$122
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-P1102
- Product descriptionTC14012 99.77%
- Packaging1mg
- Price$86
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-P1102
- Product descriptionTC14012 99.77%
- Packaging5mg
- Price$342
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-P1102
- Product descriptionTC14012 99.77%
- Packaging10mg
- Price$551
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-P1102
- Product descriptionTC14012 99.77%
- Packaging25mg
- Price$1093
- Updated2026-05-26
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1981650
- Product descriptionTC14012 TFA 96.31%
- Packaging25mg
- Price$1120
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1981650
- Product descriptionTC14012 TFA 96.31%
- Packaging10mg
- Price$740
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1981650
- Product descriptionTC14012 TFA 96.31%
- Packaging5mg
- Price$530
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1981650
- Product descriptionTC14012 TFA 96.31%
- Packaging1mg
- Price$240
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberTPA87434
- Product descriptionTC 14012
- Packaging25mg
- Price$3289
- Updated2026-06-05
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E48Y | L-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide ≥95% | 1mg | $177 | 2026-05-30 | Buy |
| aablocks | AA01E48Y | L-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide ≥95% | 5mg | $589 | 2026-05-30 | Buy |
| aablocks | AA01E48Y | L-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide ≥95% | 10mg | $824 | 2026-05-30 | Buy |
| aablocks | AA01E48Y | L-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide ≥95% | 50mg | $2884 | 2026-05-30 | Buy |
| ApexBio Technology | B7639 | TC 14012 | 10mg | $787 | 2026-05-06 | Buy |
| ApexBio Technology | B7639 | TC 14012 | 5mg | $488 | 2026-05-06 | Buy |
| ApexBio Technology | B7639 | TC 14012 | 1mg | $122 | 2026-05-06 | Buy |
| Arctom | HY-P1102 | TC14012 99.77% | 1mg | $86 | 2026-05-26 | Buy |
| Arctom | HY-P1102 | TC14012 99.77% | 5mg | $342 | 2026-05-26 | Buy |
| Arctom | HY-P1102 | TC14012 99.77% | 10mg | $551 | 2026-05-26 | Buy |
| Arctom | HY-P1102 | TC14012 99.77% | 25mg | $1093 | 2026-05-26 | Buy |
| Biorbyt Ltd | orb1981650 | TC14012 TFA 96.31% | 25mg | $1120 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1981650 | TC14012 TFA 96.31% | 10mg | $740 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1981650 | TC14012 TFA 96.31% | 5mg | $530 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1981650 | TC14012 TFA 96.31% | 1mg | $240 | 2026-05-06 | Buy |
| Biosynth | TPA87434 | TC 14012 | 25mg | $3289 | 2026-06-05 | Buy |
Properties
Density :1.554±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :Store at -80°C
solubility :Methanol (Slightly), Water (Slightly)
form :Powder
color :White to off-white
Water Solubility :Soluble to 1 mg/ml in water
Stability :Hygroscopic
storage temp. :Store at -80°C
solubility :Methanol (Slightly), Water (Slightly)
form :Powder
color :White to off-white
Water Solubility :Soluble to 1 mg/ml in water
Stability :Hygroscopic
Safety Information
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Description
C-X-C chemokine receptor type 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. TC 14012 is an antagonist of CXCR4, blocking CXCR4-mediated HIV infection with an IC50 value of 19.3 nM. In addition, TC 14012 (100 μg/ml) inhibits CXCL12-induced phosphorylation of p42/44 MAPK and STAT3 in B cells from patients with chronic lymphocytic leukemia. This peptidomimetic is C-terminally amidated, resulting in high stability in serum. TC 14012 also activates CXCR7 (EC50 = 350 nM), resulting in the recruitment of β-arrestin and Erk ? phosphorylation.Related product price
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