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ChemicalBook >> CAS DataBase List >> Valspodar

Valspodar

Valspodar price.
  • $29 - $2200
  • Product name: Valspodar
  • CAS: 121584-18-7
  • MF: C63H111N11O12
  • MW: 1214.62
  • EINECS:1312995-182-4
  • MDL Number:MFCD00907207
  • Synonyms:Valspodar;3'-Keto-bmt(1)-Val(2)-cyclosporin a;Cyclosporin A, 6-((R-(E))-6,7-didehydro-N,4-dimethyl-3-oxo-L-2-aminooctanoic acid)-7-L-valine-;Sdz psc 833;Sdz-psc-833;Cyclo[[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl]-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl];6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoicacid]-7-L-valine-cyclosporinA;Valspodar(PSC-833,AMdray)
23 prices
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Brand

  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological

Package

  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 1
  • 10mg
  • 25mg
  • 100mg
  • 250mg
  • 5 mg
  • 10 mg
  • ManufacturerAK Scientific
  • Product numberX5944
  • Product descriptionValspodar
  • Packaging5mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3905
  • Product descriptionValspodar
  • Packaging5mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3905
  • Product descriptionValspodar
  • Packaging10mg
  • Price$239
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFV28665
  • Product descriptionValspodar
  • Packaging25mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20391
  • Product descriptionPSC 833 ≥95%
  • Packaging500μg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20391
  • Product descriptionPSC 833 ≥95%
  • Packaging1mg
  • Price$55
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20391
  • Product descriptionPSC 833 ≥95%
  • Packaging5 mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20391
  • Product descriptionPSC 833 ≥95%
  • Packaging10 mg
  • Price$337
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1074
  • Product descriptionValspodar 99.27%
  • Packaging1mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1074
  • Product descriptionValspodar 99.27%
  • Packaging5mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1074
  • Product descriptionValspodar 99.27%
  • Packaging10mg
  • Price$920
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004250
  • Product descriptionValspodar 98+%
  • Packaging10mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004250
  • Product descriptionValspodar 98+%
  • Packaging5mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN12182
  • Product descriptionValspodar
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9813
  • Product descriptionValspodar(PSC833) >98%
  • Packaging100mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9813
  • Product descriptionValspodar(PSC833) >98%
  • Packaging250mg
  • Price$2200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X5944 Valspodar 5mg $320 2021-12-16 Buy
ApexBio Technology A3905 Valspodar 5mg $133 2021-12-16 Buy
ApexBio Technology A3905 Valspodar 10mg $239 2021-12-16 Buy
Biosynth Carbosynth FV28665 Valspodar 25mg $750 2021-12-16 Buy
Cayman Chemical 20391 PSC 833 ≥95% 500μg $29 2024-03-01 Buy
Cayman Chemical 20391 PSC 833 ≥95% 1mg $55 2024-03-01 Buy
Cayman Chemical 20391 PSC 833 ≥95% 5 mg $184 2024-03-01 Buy
Cayman Chemical 20391 PSC 833 ≥95% 10 mg $337 2024-03-01 Buy
ChemScene CS-1074 Valspodar 99.27% 1mg $200 2021-12-16 Buy
ChemScene CS-1074 Valspodar 99.27% 5mg $550 2021-12-16 Buy
ChemScene CS-1074 Valspodar 99.27% 10mg $920 2021-12-16 Buy
Crysdot CD31004250 Valspodar 98+% 10mg $175 2021-12-16 Buy
Crysdot CD31004250 Valspodar 98+% 5mg $98 2021-12-16 Buy
CSNpharm CSN12182 Valspodar 5mg $130 2021-12-16 Buy
DC Chemicals DC9813 Valspodar(PSC833) >98% 100mg $1100 2021-12-16 Buy
DC Chemicals DC9813 Valspodar(PSC833) >98% 250mg $2200 2021-12-16 Buy

Properties

Melting point :143-145°C
alpha :D20 -255.1° (c = 0.5 in CHCl3)
Boiling point :1290.1±65.0 °C(Predicted)
Density :1.015±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :12.45±0.70(Predicted)
form :powder
color :white to beige
InChIKey :YJDYDFNKCBANTM-QCWCSKBGSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PSC 833 is a non-immunosuppressant derivative of cyclosporine and potent multidrug-resistance (MDR) modulator. It restores sensitivity of MDR-P388 murine leukemia cells to cytostatic agents when used at concentrations of 70, 33, 45, 34, and 26 nM in combination with colchicine, vincristine , daunorubicin , doxorubicin , and etoposide , respectively. PSC 833 inhibits basal-to-apical transport and increases apical-to-basal transport of [14C]docetaxel in LLC-GA5-COLO150 cells that overexpress human P-glycoprotein (P-gp). In vivo, PSC 833 increases survival time in MDR-P388 tumor-bearing mice and in an MDR-L1210 leukemia mouse xenograft model when administered in combination with doxorubicin. PSC 833 also prolongs the anti-hyperalgesic effects of intraperitoneally administered pregabalin in a mouse model of cold stress-induced central pain.

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