XMU-MP-1
|
- $17 - $4741
- Product name: XMU-MP-1
- CAS: 2061980-01-4
- MF: C17H16N6O3S2
- MW: 416.48
- EINECS:
- MDL Number:MFCD30377214
- Synonyms:XMU-MP-1;PubChem ID: 121499143;CS-2590;4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide;Benzenesulfonamide, 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-;4-((5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino)benzenesulfonamide;XMU MP 1,Inhibitor,Hippo (MST),inhibit,XMUMP1;XUM-MP- 1
59 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Synthonix
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 10mM(1mLinDMSO)
- 2.5mg
- 10mM*1mLinDMSO(Solution)
- 10.00mg
- 50
- 25.00mg
- 10
- 50.00mg
- 1mg
- 5mg
- 10mg
- 25mg
- 1G
- 50mg
- 100mg
- 250mg
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA01E3M2
- Product descriptionXMU-MP-1 97%
- Packaging1mg
- Price$17
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E3M2
- Product descriptionXMU-MP-1 ≥98%(HPLC)
- Packaging5mg
- Price$19
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E3M2
- Product descriptionXMU-MP-1 ≥98%(HPLC)
- Packaging10mg
- Price$34
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E3M2
- Product descriptionXMU-MP-1 97%
- Packaging25mg
- Price$68
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E3M2
- Product descriptionXMU-MP-1 97%
- Packaging50mg
- Price$109
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E3M2
- Product descriptionXMU-MP-1 97%
- Packaging100mg
- Price$164
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E3M2
- Product descriptionXMU-MP-1 97%
- Packaging250mg
- Price$323
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18015
- Product descriptionXMU-MP-1 98%
- Packaging25MG
- Price$55
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18015
- Product descriptionXMU-MP-1 98%
- Packaging5MG
- Price$30
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18015
- Product descriptionXMU-MP-1 98%
- Packaging100MG
- Price$140
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL18015
- Product descriptionXMU-MP-1 98%
- Packaging1G
- Price$850
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number6147EG
- Product descriptionXmu-MP-1
- Packaging50mg
- Price$687
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8735
- Product descriptionXMU-MP-1
- Packaging25mg
- Price$429
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8735
- Product descriptionXMU-MP-1
- Packaging100mg
- Price$930
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-100526
- Product descriptionXMU-MP-1 99.93%
- Packaging50mg
- Price$618
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100526
- Product descriptionXMU-MP-1 99.93%
- Packaging100mg
- Price$803
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E3M2 | XMU-MP-1 97% | 1mg | $17 | 2026-05-30 | Buy |
| aablocks | AA01E3M2 | XMU-MP-1 ≥98%(HPLC) | 5mg | $19 | 2026-05-30 | Buy |
| aablocks | AA01E3M2 | XMU-MP-1 ≥98%(HPLC) | 10mg | $34 | 2026-05-30 | Buy |
| aablocks | AA01E3M2 | XMU-MP-1 97% | 25mg | $68 | 2026-05-30 | Buy |
| aablocks | AA01E3M2 | XMU-MP-1 97% | 50mg | $109 | 2026-05-30 | Buy |
| aablocks | AA01E3M2 | XMU-MP-1 97% | 100mg | $164 | 2026-05-30 | Buy |
| aablocks | AA01E3M2 | XMU-MP-1 97% | 250mg | $323 | 2026-05-30 | Buy |
| ACHEMBLOCK | L18015 | XMU-MP-1 98% | 25MG | $55 | 2026-05-27 | Buy |
| ACHEMBLOCK | L18015 | XMU-MP-1 98% | 5MG | $30 | 2026-05-27 | Buy |
| ACHEMBLOCK | L18015 | XMU-MP-1 98% | 100MG | $140 | 2026-05-27 | Buy |
| ACHEMBLOCK | L18015 | XMU-MP-1 98% | 1G | $850 | 2026-05-27 | Buy |
| AK Scientific | 6147EG | Xmu-MP-1 | 50mg | $687 | 2021-12-16 | Buy |
| ApexBio Technology | A8735 | XMU-MP-1 | 25mg | $429 | 2026-05-06 | Buy |
| ApexBio Technology | A8735 | XMU-MP-1 | 100mg | $930 | 2026-05-06 | Buy |
| Arctom | HY-100526 | XMU-MP-1 99.93% | 50mg | $618 | 2026-05-26 | Buy |
| Arctom | HY-100526 | XMU-MP-1 99.93% | 100mg | $803 | 2026-05-26 | Buy |
Properties
Boiling point :714.8±70.0 °C(Predicted)
Density :1.523±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :≥41.6 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :powder
pka :9.77±0.12(Predicted)
color :white to beige
InChI :InChI=1S/C17H16N6O3S2/c1-22-12-7-8-27-14(12)16(24)23(2)13-9-19-17(21-15(13)22)20-10-3-5-11(6-4-10)28(18,25)26/h3-9H,1-2H3,(H2,18,25,26)(H,19,20,21)
InChIKey :YRDHKIFCGOZTGD-UHFFFAOYSA-N
SMILES :C1(S(N)(=O)=O)=CC=C(NC2=NC=C3C(=N2)N(C)C2C=CSC=2C(=O)N3C)C=C1
Density :1.523±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :≥41.6 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :powder
pka :9.77±0.12(Predicted)
color :white to beige
InChI :InChI=1S/C17H16N6O3S2/c1-22-12-7-8-27-14(12)16(24)23(2)13-9-19-17(21-15(13)22)20-10-3-5-11(6-4-10)28(18,25)26/h3-9H,1-2H3,(H2,18,25,26)(H,19,20,21)
InChIKey :YRDHKIFCGOZTGD-UHFFFAOYSA-N
SMILES :C1(S(N)(=O)=O)=CC=C(NC2=NC=C3C(=N2)N(C)C2C=CSC=2C(=O)N3C)C=C1
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2 (IC50s = 71.1 and 38.1 nM, respectively). It is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 μM. XMU-MP-1 inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2 autophosphorylation in RAW 264.7, U2OS, SW480, RPE1, SNU423, and HepG2 cells in a concentration-dependent manner. It also prevents cell death induced by overexpression of MST2. XMU-MP-1 (1 mg/kg) enhances liver regeneration in mice post partial hepatectomy and reduces liver fibrosis in a mouse model of chronic liver injury.Related product price
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