ZOTAROLIMUS
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- $36 - $4900
- Product name: ZOTAROLIMUS
- CAS: 221877-54-9
- MF: C52H79N5O12
- MW: 966.21
- EINECS:
- MDL Number:MFCD09752954
- Synonyms:ZOTAROLIMUS;(42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin;A 179578;ABT 578;Rapamycin, 42-deoxy-42-(1H-tetrazol-1-yl)-, (42S)-;Unii-H4gxr80ize;ZotaroliMus, >90%;42-(1-Tetrazolyl)rapamycin
46 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25MG
- 100MG
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00BF5C
- Product descriptionZotarolimus ≥95%(mixtureofisomers)
- Packaging1mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF5C
- Product descriptionZotarolimus
- Packaging10mg
- Price$122
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF5C
- Product descriptionZotarolimus
- Packaging5mg
- Price$81
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16067
- Product descriptionABT 578 98%
- Packaging5MG
- Price$125
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16067
- Product descriptionABT 578 98%
- Packaging25MG
- Price$385
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16067
- Product descriptionABT 578 98%
- Packaging100MG
- Price$775
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX7264
- Product descriptionZatarolimus
- Packaging25mg
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7264
- Product descriptionZatarolimus
- Packaging5mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004662
- Product descriptionZOTAROLIMUS 95.00%
- Packaging1MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004662
- Product descriptionZOTAROLIMUS 95.00%
- Packaging10MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSLK-S7091
- Product descriptionZotarolimus (ABT-578) Purity:>97%
- Packaging25mg
- Price$473
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S7091
- Product descriptionZotarolimus (ABT-578) Purity:>97%
- Packaging5mg
- Price$188
- Updated2026-05-26
- Buy
- ManufacturerAvaChem
- Product number4696
- Product descriptionZotarolimus
- Packaging25mg
- Price$249
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number4696
- Product descriptionZotarolimus
- Packaging100mg
- Price$790
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number4696
- Product descriptionZotarolimus
- Packaging10mg
- Price$129
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number4696
- Product descriptionZotarolimus
- Packaging5mg
- Price$69
- Updated2026-05-22
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BF5C | Zotarolimus ≥95%(mixtureofisomers) | 1mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00BF5C | Zotarolimus | 10mg | $122 | 2026-05-28 | Buy |
| aablocks | AA00BF5C | Zotarolimus | 5mg | $81 | 2026-05-28 | Buy |
| ACHEMBLOCK | R16067 | ABT 578 98% | 5MG | $125 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16067 | ABT 578 98% | 25MG | $385 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16067 | ABT 578 98% | 100MG | $775 | 2026-05-27 | Buy |
| AK Scientific | X7264 | Zatarolimus | 25mg | $590 | 2021-12-16 | Buy |
| AK Scientific | X7264 | Zatarolimus | 5mg | $239 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004662 | ZOTAROLIMUS 95.00% | 1MG | $750.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004662 | ZOTAROLIMUS 95.00% | 10MG | $1963.5 | 2021-12-16 | Buy |
| Arctom | SLK-S7091 | Zotarolimus (ABT-578) Purity:>97% | 25mg | $473 | 2026-05-26 | Buy |
| Arctom | SLK-S7091 | Zotarolimus (ABT-578) Purity:>97% | 5mg | $188 | 2026-05-26 | Buy |
| AvaChem | 4696 | Zotarolimus | 25mg | $249 | 2026-05-22 | Buy |
| AvaChem | 4696 | Zotarolimus | 100mg | $790 | 2026-05-22 | Buy |
| AvaChem | 4696 | Zotarolimus | 10mg | $129 | 2026-05-22 | Buy |
| AvaChem | 4696 | Zotarolimus | 5mg | $69 | 2026-05-22 | Buy |
Properties
Melting point :100-105°C
Boiling point :1016.2±75.0 °C(Predicted)
Density :1.25
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO, Methanol (Slightly)
form :Solid
pka :10.40±0.70(Predicted)
color :White to Pale Yellow
InChIKey :CGTADGCBEXYWNE-JUKNQOCSSA-N
Boiling point :1016.2±75.0 °C(Predicted)
Density :1.25
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO, Methanol (Slightly)
form :Solid
pka :10.40±0.70(Predicted)
color :White to Pale Yellow
InChIKey :CGTADGCBEXYWNE-JUKNQOCSSA-N
Safety Information
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Description
Zotarolimus is a macrocyclic lactone immunosuppressant and a derivative of rapamycin . It binds to FKBP prolyl isomerase 1A (FKBP12; IC50 = 2.57 nM) and inhibits proliferation of human peripheral blood mononuclear cells (PBMCs), rat splenocytes, and human coronary artery smooth muscle cells (IC50s = 7, 1,337, and 0.8 nM, respectively). Zotarolimus has immunosuppressive activity in a one-way mixed lymphocyte reaction using human or rat lymphocytes (IC50s = 1.2 and 1,465 nM, respectively). It also reduces symptom severity in a rat model of experimental autoimmune encephalomyelitis (EAE; ED50 = 1.17 mg/kg per day) and delays cardiac allograft rejection in rats (ED50 = 3.71 mg/kg per day). Zotarolimus inhibits neointimal formation and reduces stenosis in pig coronary arteries when applied at 10 μg/mm to stainless steel balloon expandable stents with phosphorylcholine in a model of restenosis. Formulations containing zotarolimus have been used in drug-eluting stents in the prevention of restenosis following stent placement.Related product price
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Suppliers and manufacturers
J & K SCIENTIFIC LTD.
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AdooQ BioScience, LLC
Jinan Mingya Medical Technology Co., Ltd.
ShangHai Caerulum Pharma Discovery Co., Ltd.
HBCChem, Inc.