Antiepileptic and anticonvulsant

Anticonvulsants are clinically used in children with high fever, eclampsia, tetanus, grand mal seizures, and excessive central excitation caused by certain medicine. With a strong inhibitory effect on the central nervous system, they are a class of drugs that can remit or relieve the symptoms of seizures and used in the treatment of convulsions caused by various effects, such as eclampsia, tetanus, grand mal seizures and central stimulant poisoning. Barbiturates such as phenobarbital, benzodiazepines such as clozapine, diazepam, nitrazepam and chloral hydrate, dilantin, magnesium sulfate injection are commonly used anticovulsants.

Epilepsy is a chronic, reduplicative, paroxysmal central nervous system disease, characterized by the sudden abnormal bursts of high-frequency discharge of brain nerves and the sequential spread to the surrounding. Antiepileptics belong to anticonvulsants, used for the treatment of epilepsy. Antiepileptic drug is a symptomatic treatment for pilepsy patients to control the symptoms, so the patients must accept long-term medication. Antiepileptics stop seizures in two ways, in one of which they directly act on the brain tissue local epilepsy lesions, reducing the excessive discharge; in the other of which they act on the normal brain tissue around the lesion to prevent the spread of abnormal discharge. Phenytoin, phenobarbital, deoxybenzene, ethosuximide, carbamazepine, sodium valproate and benzodiazepines are commonly used antiepileptics.

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Structure Chemical Name CAS MF
LACOSAMIDE LACOSAMIDE 175481-36-4 C13H18N2O3
Levetiracetam Levetiracetam 102767-28-2 C8H14N2O2
2-Propylpentanoic acid 2-Propylpentanoic acid 99-66-1 C8H16O2
Topiramate Topiramate 97240-79-4 C12H21NO8S
Vanillin Vanillin 121-33-5 C8H8O3
Oxcarbazepine Oxcarbazepine 28721-07-5 C15H12N2O2
Zonisamide Zonisamide 68291-97-4 C8H8N2O3S
Carbamazepine Carbamazepine 298-46-4 C15H12N2O
Piperine Piperine 94-62-2 C17H19NO3
Pregabalin Pregabalin 148553-50-8 C8H17NO2
Gabapentin Gabapentin 60142-96-3 C9H17NO2
Riluzole Riluzole 1744-22-5 C8H5F3N2OS
Phenytoin sodium Phenytoin sodium 630-93-3 C15H11N2NaO2
5,5-Diphenylhydantoin 5,5-Diphenylhydantoin 57-41-0 C15H12N2O2
Fenasi Fenasi
Sodium 2-propylpentanoate Sodium 2-propylpentanoate 1069-66-5 C8H15NaO2
Lamotrigine Lamotrigine 84057-84-1 C9H7Cl2N5
Felbamate Felbamate 25451-15-4 C11H14N2O4
(S)-MEPHENYTOIN (S)-MEPHENYTOIN 50-12-4 C12H14N2O2
ETHOTOIN ETHOTOIN 86-35-1 C11H12N2O2
MAGNESIUM DIPROPYLACETATE HYDRATE MAGNESIUM DIPROPYLACETATE HYDRATE 62959-43-7 C16H30MgO4
Primidone Primidone 125-33-7 C12H14N2O2
VIGABATRIN VIGABATRIN 60643-86-9 C6H11NO2
Progabide Progabide 62666-20-0 C17H16ClFN2O2
ETHOSUXIMIDE ETHOSUXIMIDE 77-67-8 C7H11NO2
fluoresone fluoresone 2924-67-6 C8H9FO2S
PHENYLACETYLUREA PHENYLACETYLUREA 63-98-9 C9H10N2O2
METHSUXIMIDE METHSUXIMIDE 77-41-8 C12H13NO2
3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE 3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE 127-48-0 C6H9NO3
PHENSUXIMIDE PHENSUXIMIDE 86-34-0 C11H11NO2
2,2-DI-N-PROPYLACETAMIDE 2,2-DI-N-PROPYLACETAMIDE 2430-27-5 C8H17NO
piperine piperine 7780-20-3 C17H19NO3
doxenitoin  doxenitoin 3254-93-1 C15H14N2O
PARAMETHADIONE (500 MG) PARAMETHADIONE (500 MG) 115-67-3 C7H11NO3
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