Ophthalmic drugs

Ophthalmic drugs currently used in the outpatient include antibiotics (antibacterial agents), steroids, glaucoma, cataracts, artificial tears and anti-allergic drugs and so on. As the ophthalmic drugs are directly used in the eye surface to effect, so the efficacy is of course direct and fast. Most people will not have a special reaction, but for the people sensitive to the drugs, a drop of eye drops may cause allergies, increased intraocular pressure, asthma, irregular heartbeat and systemic side effects, so the use of eye drops should be very cautious.

Visual organs is one of the important organs of the body, and the treatment of eye disease should have a overall concept. Systemic disease or localized lesions far away from eyes are likely factors to cause eye disease; similarly, the treatment of eye diseases may also affect the whole body condition.

Due to the presence of blood-ocular barriers, including blood-water barrier, blood-retinal barrier (BRB) and other special tissue anatomical structures, effective drug treatment for most eye diseases is the local drug delivery. Therefore, a considerable understanding of the local pharmacokinetics and pharmacodynamics of ophthalmic drugs is indispensable in addition to the strict control of indications for the rational drug use.

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Structure Chemical Name CAS MF
Micafungin Micafungin 235114-32-6 C56H71N9O23S
Tropicamide Tropicamide 1508-75-4 C17H20N2O2
Caspofungin Caspofungin 162808-62-0 C52H88N10O15
Methyl cellulose Methyl cellulose 9004-67-5 C20H38O11
Caspofungin acetate Caspofungin acetate 179463-17-3 C54H92N10O17
Alprenoxime hydrochloride Alprenoxime hydrochloride 121009-30-1 C15H23ClN2O2
3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride 3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride 15148-80-8 C14H22ClNO2.ClH
Brovincamine Fumarte Brovincamine Fumarte 84964-12-5 C21H25BrN2O3.C4H4O4
Retin-20,20,20-d3-ol, 15-acetate Retin-20,20,20-d3-ol, 15-acetate 118139-36-9 C22H32O2
MetipranololHydrochloride MetipranololHydrochloride 36592-77-5 C17H28ClNO4
Aganepag (Synonyms: AGN 210937) Aganepag (Synonyms: AGN 210937) 910562-18-4 C24H31NO4S
Pilocarpine borate Pilocarpine borate 16509-56-1 C11H19BN2O5
formocortal formocortal 2825-60-7 C29H38ClFO8
1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j′]diquinolizin-18-ium, 9-[2(or 4)-[[[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]sulfonyl]-4(or 2)-sulfophenyl]-2,3,6,7,12,13,16,17-octahydro-, inner salt (9CI, ACI) 1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j′]diquinolizin-18-ium, 9-[2(or 4)-[[[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]sulfonyl]-4(or 2)-sulfophenyl]-2,3,6,7,12,13,16,17-octahydro-, inner salt (9CI, ACI) 849758-52-7
PF-4217329 PF-4217329 1005549-94-9 C27H28N4O5S
Micafungin sodium Micafungin sodium 208538-73-2 C56H72N9NaO23S
adaprolol adaprolol 121009-31-2 C30H43NO8
ROSTAPORFIN ROSTAPORFIN 284041-10-7 C37H42Cl2N4O2Sn
AGN 210676 AGN 210676 910562-15-1 C23H29NO5S
Aganepag ethanediol Aganepag ethanediol 1192760-33-0 C26H35NO5S
Hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester Hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester 1194396-71-8 C31H46N2O8
Timolol hemihydrate Timolol hemihydrate 91524-16-2 C26H50N8O7S2
Bupranolol Bupranolol 14556-46-8 C14H22ClNO2
Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester, compd. with 3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one (1:) Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester, compd. with 3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one (1:) 91283-98-6 C37H40N2O8
Verosudil Hydrochloride Verosudil Hydrochloride 1414854-44-6 C17H18ClN3O2S
Cenegermin Cenegermin 1772578-74-1
Besifovir Besifovir 1254032-66-0 C28H27N3O3
Armin Armin 546-71-4 C10H14NO5P
Urcosimod Urcosimod 1610366-43-2 C101H152N14O27
Orvepitant Orvepitant 1262873-06-2 C26H36F2O6
4H-Thieno[2,3-b]thiopyran-2-sulfonamide,5,6-dihydro-4-[(2-methylpropyl)amino]-, 7,7-dioxide, hydrochloride (1:1), (4S)- 4H-Thieno[2,3-b]thiopyran-2-sulfonamide,5,6-dihydro-4-[(2-methylpropyl)amino]-, 7,7-dioxide, hydrochloride (1:1), (4S)- 119271-78-2 C11H19ClN2O4S3
Evodenoson Evodenoson 844873-47-8 C23H29N7O6
Simenepag isopropyl Simenepag isopropyl 910562-13-9 C26H35NO5S
MEDRYSONE MEDRYSONE 2668-66-8 C22H32O3
Ibopamine Hydrochloride Ibopamine Hydrochloride 75011-65-3 C17H26ClNO4
Abicipar pegol Abicipar pegol 1327278-94-3
Verosudil Verosudil 1414854-42-4 C17H17N3O2S
Lampalizumab Lampalizumab 1278466-20-8
ECOTHIOPATE IODIDE ECOTHIOPATE IODIDE 513-10-0 C9H23INO3PS
Anidulafungin Anidulafungin 166663-25-8 C58H73N7O17
Bunolol Bunolol 31969-05-8 C17H26ClNO3
Pirnabine Pirnabine 19825-63-9 C19H24O3
Dorzolamide/timolol combination Dorzolamide/timolol combination 146235-46-3 C23H40N6O7S4
(R)-3-amino-1-(3-(cyclohexylmethoxy)phenyl)propan-1-ol (R)-3-amino-1-(3-(cyclohexylmethoxy)phenyl)propan-1-ol 1141777-14-1 C16H25NO2
Pegaptanib Sodium Pegaptanib Sodium 222716-86-1 C22H44N3O10P
Aganepag isopropyl Aganepag isopropyl 910562-20-8 C27H37NO4S
Befunolol hydrochloride Befunolol hydrochloride 39543-79-8 C16H22ClNO4
endrisone endrisone 35100-44-8 C22H30O3
Brimonidine Brimonidine 59803-98-4 C11H10BrN5
berefrine berefrine 105567-83-7 C14H21NO2
Parotin Parotin 1392-81-0
Ripasudil Ripasudil 223645-67-8 C15H18FN3O2S
Afuresertib Afuresertib 515138-06-4 C25H23F3N2O4S
CYCLOPENTOLATE CYCLOPENTOLATE 512-15-2 C17H25NO3
2-HYDROXY-N,N,N,N',N',N'-HEXAMETHYL-1,3-PROPANE DIAMINIUM DI IODIDE 2-HYDROXY-N,N,N,N',N',N'-HEXAMETHYL-1,3-PROPANE DIAMINIUM DI IODIDE 123-47-7 C9H24I2N2O
MTS Reagent MTS Reagent 138169-43-4 C20H17N5O6S2
Pirenoxine Pirenoxine 1043-21-6 C16H8N2O5
Apraclonidine Apraclonidine 66711-21-5 C9H10Cl2N4
1-HYDROXY-5-OXO-5H-PYRIDO[3,2-A]PHENOXAZINE-3-CARBOXYLIC ACID MONOSODIUM SALT 1-HYDROXY-5-OXO-5H-PYRIDO[3,2-A]PHENOXAZINE-3-CARBOXYLIC ACID MONOSODIUM SALT 51410-30-1 C16H7N2NaO5
Dipivefrin hydrochloride Dipivefrin hydrochloride 64019-93-8 C19H30ClNO5
Hydrobenzole Hydrobenzole
Copper citrate Copper citrate 866-82-0 C6H8CuO7
Apraclonidine hydrochloride Apraclonidine hydrochloride 73218-79-8 C9H11Cl3N4
Brolucizumab Brolucizumab 1531589-13-5
rac Mepindolol-d7 rac Mepindolol-d7 23694-81-7 C15H22N2O2
Avacincaptad pegol sodium Avacincaptad pegol sodium 1491144-00-3
Volociximab Volociximab 558480-40-3
Azapentacene Azapentacene 3863-80-7 C18H10N4Na2O6S2
ESERINE SULFATE ESERINE SULFATE 64-47-1 C30H44N6O8S
Dapiprazole Dapiprazole 72822-12-9 C19H27N5
Verteporfin Verteporfin 129497-78-5 2C41H42N4O8
Dipivefrine Dipivefrine 52365-63-6 C19H29NO5
Bromfenac monosodium salt sesquihydrate Bromfenac monosodium salt sesquihydrate 120638-55-3 C15H11BrNNaO3
EUCATROPINE HYDROCHLORIDE EUCATROPINE HYDROCHLORIDE 536-93-6 C17H26ClNO3
NCX 116 NCX 116 860005-21-6 C27H41NO8
ACETAZOLAMIDE SODIUM ACETAZOLAMIDE SODIUM 1424-27-7 C4H7N4NaO3S2
Omidenepag Omidenepag 1187451-41-7 C23H22N6O4S
furtrethonium iodide furtrethonium iodide 541-64-0 C8H14INO
DIISOPROPYL FLUOROPHOSPHATE DIISOPROPYL FLUOROPHOSPHATE 55-91-4 C6H14FO3P
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