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Tropicamide Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Products Intro: Product Name:Tropicamide
Purity:99% Package:11000/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Tropicamide
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:1508-75-4
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Tropicamide
Company Name: Nanjing Finetech Chemical Co., Ltd.
Tel: 025-85710122 17714198479
Products Intro: Product Name:Tropicamide
Purity:99%min Package:1KG;10KG;100KG;500KG;100g Remarks:ISO certified

Lastest Price from Tropicamide manufacturers

  • Tropicamide
  • US $100.00 / KG
  • 2018-08-02
  • CAS:1508-75-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: Customized
Tropicamide Basic information
Ophthalmic drugs Uses
Product Name:Tropicamide
Synonyms:Tropicamide WS;Benzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-;bistropamide;component of Paremyd;epitromina;Mydriacyl;mydriat;mydrin
Product Categories:Inhibitors;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Acetylcholine receptor
Mol File:1508-75-4.mol
Tropicamide Structure
Tropicamide Chemical Properties
Melting point 98 °C
storage temp. 2-8°C
solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/mL
form solid
pkapKa 5.3 (Uncertain)
color white
λmax254nm(HCl aq.)(lit.)
Merck 14,9780
CAS DataBase Reference1508-75-4(CAS DataBase Reference)
NIST Chemistry ReferenceTropicamide(1508-75-4)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/21/22-36/37/38-42/43-41-37/38-22
Safety Statements 22-26-36-36/37/39
WGK Germany 3
RTECS CY1487860
MSDS Information
Tropicamide Usage And Synthesis
Ophthalmic drugsTropicamide is an anticholinergic agent. At room temperature, it is a white crystalline powder and is odorless. It is slightly soluble in water and easily soluble in ethanol, dilute hydrochloric acid, sulfuric acid and chloroform. It can block the excitement of iris sphincter and ciliary muscle induced by acetylcholine. Its 0.5% solution can cause mydriasis while its 1% solution can cause ciliary muscle paralysis and mydriasis. Clinically it is mainly used for the treatment of eye drops mydriasis and paralysis.
Tropicamide is the synthetic derivative of tropic acid. It has a relative low dissociation constant with good intraocular permeability and strong tissue diffusion capability which may be the underlying mechanism for its quick onset but short maintaining time. After the drop of the 0.5% or 1% solution of this product, the instillation dilation and paralysis adjustment can reach peak within 20-30 minutes. Then the effect gradually decreases with adjusting paralysis (residual) for 2 to 6 hours and mydriasis (residual) for about 7 hours. Tropicamide is similar drug as atropine which can cause a dramatic increase on the angle closure glaucoma intraocular pressure as well as possibly stimulate undiagnosed angle-closure glaucoma.
The potency of ciliary muscle paralysis adjustment of tropicamide eye drops is closely related with the doses used, its 0.25%, 0.5%, 0.75% and 1% four concentrations can all adjust paralysis. After instillation, the maximum degree of residual adjustment is 0.25%: diopter: 3.17; 1% diopter: 3.17. The residue adjustment degree can be maintained in cases of the refraction being 2.0 or less, 0.75% and 1% solutions can maintain for 40 minutes while 0.5% can only maintain about 15 minutes. After a drop of 1% solution, have the second drop after 5 to 25 minutes and by doing this, we can get more satisfactory ciliary muscle paralysis effect for about 20 to 30 minutes. After 2 to 6 hours, you can read books and newspapers with the adjustment function being able to recover to the level before drop within 6 hours.
The above information is edited by the Chemicalbook of Dai Xiongfeng.
UsesIt can be used as an anti-cholinergic drugs or mydriatic drug.
It is a kind of M4 muscarinic acetylcholine receptor antagonist.
Chemical PropertiesCrystalline Solid
Usesantidepressant, nutrient; LD50(rat) 1634 mg/kg ip
UsesIndicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.
UsesOphthalmic anticholinergic. Mydriatic
Brand nameMydriacyl (Alcon); Tropicacyl (Akorn).
Biological ActivityM 4 selective muscarinic receptor antagonist.
Tropicamide Preparation Products And Raw materials
Tag:Tropicamide(1508-75-4) Related Product Information
CHEMBRDG-BB 9070906 METHYLPYRIDIN-4-YLMETHYLAMINE N,N-DIETHYL-2-PHENYLACETAMIDE N-(pyridin-4-ylmethyl)propan-1-amine Tropicamide Phenylacetic acid PHENYL RESIN Sodium isethionate Boc-D-Glutamine cis-13-Docosenoamide 4-Ethylpyridine Formamide Phenyl salicylate Acrylamide 2-(2-Aminoethylamino)ethanol Ethylparaben Diphenyl ether Polyacrylamide