| Company Name: |
ShangHai Anpel Co, Ltd.
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| Tel: |
18501792038; 18501792038 |
| Email: |
shanpel@anpel.com.cn |
| Products Intro: |
Cas:375-22-4
ProductName:Perfluorobutanoic acid
Purity: 标准品 | Package: 100mg
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| Company Name: |
Wuhan Hongde Yuexin Pharmatech Co.,Ltd
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| Tel: |
027-83850116 18164090116 |
| Email: |
whhdyxchem123@sina.com |
| Products Intro: |
Cas:375-22-4
ProductName:heptafluorobutyric acid
Purity: 99% HPLC | Package: 25kg：100kg
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| Company Name: |
SynQuest Laboratories, Inc.
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| Tel: |
904 462 0788 |
| Email: |
info@synquestlabs.com |
| Products Intro: |
Cas:375-22-4
ProductName:Heptafluorobutyric acid
Brand: SynQuest Laboratories | Product Number: 2121-3-34 | Purity: 98%
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| Company Name: |
Hubei chengfeng chemical co. LTD
|
| Tel: |
15827338311 |
| Email: |
1802085297@qq.com |
| Products Intro: |
Cas:375-22-4
ProductName:Heptafluorobutyric acid
Purity: 99% | Package: 1KG;5KG；25KG；200KG；T
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| | Perfluorobutanoic Acid Basic information |
| | Perfluorobutanoic Acid Chemical Properties |
| Melting point | -17.5 °C | | Boiling point | 120 °C755 mm Hg(lit.) | | density | 1.645 g/mL at 25 °C(lit.) | | vapor density | 7 (vs air) | | vapor pressure | ~10 mm Hg ( 25 °C) | | refractive index | n20/D 1.3(lit.) | | Fp | 120-121°C | | storage temp. | Store below +30°C. | | solubility | Chloroform: soluble; Methanol: soluble | | form | Powder | | pka | pK1:0.17 (25°C) | | Specific Gravity | approximate 1.6 | | color | Clear colorless to faint yellow | | PH | 1 (H2O, 20℃) | | Water Solubility | miscible | | Sensitive | Light Sensitive | | BRN | 1426882 | | InChIKey | YPJUNDFVDDCYIH-UHFFFAOYSA-N | | CAS DataBase Reference | 375-22-4(CAS DataBase Reference) | | NIST Chemistry Reference | Butanoic acid, heptafluoro-(375-22-4) | | EPA Substance Registry System | Heptafluorobutyric acid (375-22-4) |
| Hazard Codes | C | | Risk Statements | 34-35 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3265 8/PG 2 | | WGK Germany | 3 | | RTECS | ET4025000 | | F | 3-8-10 | | Hazard Note | Corrosive | | TSCA | T | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29159000 |
| | Perfluorobutanoic Acid Usage And Synthesis |
| Chemical Properties | Clear colorless to faintly yellow liquid | | Uses | Perfluorobutyric acid was used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It was used as ion pairing reagent in preparative and analytical reserved phase HPLC of underivatised peptides. | | Uses | Heptafluorobutyric acid (HBFA) has been used widely for purifying neuropeptides because of its excellent resolution. The use of heptafluorobutyric acid as a volatile ion-pair reagent in the high-performance liquid chromatographic isolation of SB-223070 John K.
Heptafluorobutyric acid is a strong acid and ion-pairing agent that is used in analytical chemistry, notably in HPLC and in gas chromatography/mass spectrometry (GC/MS), in a similar manner to trifluoroacetic acid (TFA). The strong acidity of HFBA ensures that other acidic groups such as carboxylic acid moieties on biomolecules remain protonated, and thus the biomolecule samples are able to interact with organic solvents in such processes as reverse phase chromatography. The longer alkyl chain of HFBA makes it more hydrophobic than TFA, and thus HFBA can be utilized with more hydrophobic samples.
HFBA (0.1%) has been used in the mobile phase of an HPLC/LC-MS protocol for the detection of marine bacterioplankton sideophores.A study of the effects of various acids, including HFBA, on the resolution of intact proteins by reversed-phase LC/ESI-MS has been published.A modified version of the peptide ladder sequencing technique that incorporates allyl isothiocyanate and HFBA has been reported. | | Uses | Heptafluorobutyric acid is an ion pair reagent for reverse-phase HPLC. It is used in the sequencing, synthesis, and solubilizing of proteins and peptides. It is used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It is an effective additive for zinc electrodeposition. | | Definition | ChEBI: A monocarboxylic acid that is perfluorinated butyric acid. | | General Description | Perfluorobutyric acid is an effective additive for zinc electrodeposition. | | Hazard | Irritant to tissue. | | Purification Methods | Fractionally distil the acid twice in an Oldershaw column (p 10) with an automatic vapour-dividing head, the first distillation being in the presence of conc H2SO4 as a drying agent. (Take care with the hot acid.) [Beilstein 2 IV 810.] |
| | Perfluorobutanoic Acid Preparation Products And Raw materials |
| Raw materials | Perfluoropropionic acid-->Cyclopropanecarboxylic acid, 2,2,3,3-tetrafluoro-1-(trifluoromethyl)--->PERFLUOROPENTANOIC ACID-->Perfluorohexanoic acid-->Pentadecafluorooctanoic acid-->Pivaloyl chloride-->Trifluoroacetic acid-->Perfluoroheptanoic acid-->HEXAMETHYLACETONE-->Butanamide, 2,2,3,3,4,4,4-heptafluoro-N-(2,2,3,3,4,4,4-heptafluoro-1-oxobutyl)--->1H-HEPTAFLUOROPROPANE | | Preparation Products | N-Heptafluorobutyrylimidazole-->Heptafluorobutyric anhydride |
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