- motesanib
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- $15.00 / 1KG
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2021-07-02
- CAS:453562-69-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Motesanib
-
- $1.00 / 1g
-
2020-01-03
- CAS:453562-69-1
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100kgs
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| | Motesanib Basic information |
| Product Name: | Motesanib | | Synonyms: | N-(3,3-diMethylindolin-6-yl){2-[(4-pyridylMethyl)-aMino](3-pyridyl)}-carboxaMide;3-PyridinecarboxaMide, N-(2,3-dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-;Motesanib Base;AMG-706(Motesanib);Motesanib (AMG-706) Base);motesanib;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide | | CAS: | 453562-69-1 | | MF: | C22H23N5O | | MW: | 373.45 | | EINECS: | | | Product Categories: | API;Inhibitors;Antineoplastic | | Mol File: | 453562-69-1.mol |  |
| | Motesanib Chemical Properties |
| Melting point | 147-150°C | | Boiling point | 517.3±50.0 °C(Predicted) | | density | 1.251 | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | White powder solid. | | pka | 11.75±0.40(Predicted) | | color | Pale Yellow |
| | Motesanib Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively. | | Uses | Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma. | | Definition | ChEBI: Motesanib is a pyridinecarboxamide. | | target | VEGFR1 |
| | Motesanib Preparation Products And Raw materials |
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