鸢尾苷
| 中文名称 | 鸢尾苷 |
|---|---|
| 中文同义词 | 鸢尾黄酮,鸢尾苷元,射干苷元;鸢尾苷元磺酸钠;鸢尾黄素(鸢尾黄酮,鸢尾苷元,射干苷元);TECTORIGENIN 鸢尾黄素;5,7-二羟基-3-(4-羟基苯基)-6-甲氧基-4H-1-苯并吡喃-4-酮;鸢尾黄素(标准品);鸢尾黄酮;射干苷元 |
| 英文名称 | Tectorigenin |
| 英文同义词 | Tectorigenin 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one;4',5,7-Trihydroxy-6-methoxyisoflavone;Tectorigenine;Tectrigenin |
| CAS号 | 548-77-6 |
| 分子式 | C16H12O6 |
| 分子量 | 300.26 |
| EINECS号 | |
| 相关类别 | 中药对照品;标准品;对照品,标准品;分析标准品;植物提取物;中药标准品;对照品;植提标准品;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;分析试剂标准品;标准品-对照品;标准品-中药标准品;黄酮;标准品 -中药标准品;分析试剂-标准品;标准品，对照品;高纯分离试剂-标准品;化工中间体;植物单体 |
| Mol文件 | 548-77-6.mol |
| 结构式 |  |
鸢尾苷 性质
| 熔点 | 225-226° |
|---|---|
| 沸点 | 361.5°C (rough estimate) |
| 密度 | 1.512 |
| 折射率 | 1.4600 (estimate) |
| 储存条件 | Sealed in dry,2-8°C |
| 溶解度 | DMSO：150 mg/mL（499.57 mM；需要超声波和加热） |
| 形态 | 粉末晶体 |
| 酸度系数(pKa) | 6.49±0.20(Predicted) |
| 颜色 | 白色至橙色再至绿色 |
| BRN | 305601 |
| CAS 数据库 | 548-77-6 |
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth. Palmitic acid (PA)-stimulated ROS production is abolished by treatment with Tectorigenin for HUVECs in a dose-dependent manner (0.1, 1, 10 μM). Treatment with Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. Tectorigenin treatment also effectively inhibits PA-augmented TNF-α and IL-6 production in a concentration dependent manner. The number of viable HepG2 cells treated by Tectorigenin decreases in a concentration- and time-dependent manner. When HepG2 cells are treated with Tectorigenin at 5, 10 and 20 mg/L for 24 h, the viability rate is 91%, 79% and 62%, respectively.
药理药效:具有清热解毒、利咽消痰、散血消肿的功效
安全信息
| WGK Germany | 3 |
|---|---|
| RTECS号 | NR2400000 |
| 海关编码 | 2932.99.6100 |