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| | C00984 Chemical Properties |
| Melting point | 169-170oC | | Boiling point | 410.8±45.0 °C(Predicted) | | density | 1.732±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator, Under Inert Atmosphere | | solubility | Water (Slightly) | | pka | 12.12±0.70(Predicted) | | form | Solid | | color | White to Off-White | | Major Application | pharmaceutical (small molecule) | | InChI | 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6+/m1/s1 | | InChIKey | WQZGKKKJIJFFOK-PHYPRBDBSA-N | | SMILES | O1[C@@H]([C@@H]([C@H]([C@H]([C@H]1CO)O)O)O)O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | C00984 Usage And Synthesis |
| Uses | α-D-Galactose is the alpha anomer of D-Galactose (G155250), the C-4 epimer of Glucose (G595000). D-Galactose is found in milk and sugar beets as well as being synthesized by the body. | | Definition | ChEBI: Alpha-D-galactose is d-Galactopyranose having alpha-configuration at the anomeric centre. It has a role as a mouse metabolite. It is an enantiomer of an alpha-L-galactose. | | IC 50 | Human Endogenous Metabolite | | Purification Methods | -D-Galactose is crystallised twice from aqueous 80% EtOH at -10o, then dried in a vacuum oven at 90o over P2O5 for 10hours. [Link Biochemical Preparations 3 75 1953, Hansen et al. Biochemical Preparations 4 2 1955.] Also purify it by recrystallising the dried solid (150g) in hot H2O (150mL), then adding hot MeOH (250mL) and hot EtOH (500mL), stirring to mix, filtering through a bed of charcoal, and the clear filtrate is stirred to initiate crystallisation. After standing overnight at 10o, the crystals of the -anomer are filtered off by suction, washed with MeOH, then EtOH, and dried (yield 130g), and more can be obtained by evaporation of the filtrate and washing as before. [Wolfrom & Thompson Methods in Carbohydrate Chemistry I 120 1962, Academic Press, Beilstein 1 IV 4336.] |
| | C00984 Preparation Products And Raw materials |
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