|
|
| | WAY100635 Basic information |
| Product Name: | WAY100635 | | Synonyms: | Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1);WAY-100635 (maleate) N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide, 2Z-butenedioate;WAY100635 100MG;CS-998;WAY100635 USP/EP/BP;PectDrill;Superthiol sirup;WAY-100635 Monomaleate | | CAS: | 1092679-51-0 | | MF: | C29H38N4O6 | | MW: | 538.65 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1092679-51-0.mol |  |
| | WAY100635 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | ≥53.9 mg/mL in DMSO; ≥51.2 mg/mL in EtOH; ≥6.08 mg/mL in H2O with ultrasonic | | form | solid | | color | White to off-white | | Water Solubility | Soluble to 25 mM in water |
| | WAY100635 Usage And Synthesis |
| Description | WAY-100635 is a potent, silent antagonist of serotonin 5-HT1A receptors with an IC50 value of 2.2 nM (Ki = 0.8 nM) for inhibiting 5-HT1A receptors in rat hippocampal membranes. Because it displays 100-fold selectivity for 5-HT1A over other 5-HT subtypes, WAY-100635 is classically used to examine the distribution and function of 5-HT1A receptors. However, WAY-100635 has also been shown to exhibit agonist activity at dopamine D4 receptors (Kd = 2.4 nM). | | storage | Desiccate at RT |
| | WAY100635 Preparation Products And Raw materials |
|