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| | Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl Basic information |
| Product Name: | Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl | | Synonyms: | METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE;METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL;METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HYDROCHLORIDE;CHEMBRDG-BB 4003545;N-METHYL-N-TETRAHYDRO-2H-PYRAN-4-YLAMINE;N-METHYL-TETRAHYDRO-2H-PYRAN-4-AMINE;N-METHYL-TETRAHYDRO-2H-PYRAN-4-AMINE HYDROCHLORIDE;4-(Methylamino)tetrahydro-2H-pyran | | CAS: | 220641-87-2 | | MF: | C6H13NO | | MW: | 115.17 | | EINECS: | 205-516-1 | | Product Categories: | | | Mol File: | 220641-87-2.mol |  |
| | Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl Chemical Properties |
| Boiling point | 165.0±33.0 °C(Predicted) | | density | 0.93±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 10.01±0.20(Predicted) | | form | liquid | | color | Clear, colourless |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-22 | | Safety Statements | 26-36/37/39 | | RIDADR | UN2735 | | Hazard Note | Harmful | | HazardClass | IRRITANT | | HS Code | 2932990090 |
| | Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl Usage And Synthesis |
| Uses |
Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl is mainly used in dyes, pesticides, etc., but also food additives, flavours, and fragrances.
| | Synthesis | To a stirred solution of tetrahydro-4H-pyran-4-one (1 g, 10 mmol) in tetrahydrofuran (THF, 10 mL) was added slowly and dropwise at room temperature methylamine (0.62 g, 20 mmol, 2 M THF solution), followed by acetic acid (0.5 mL). The reaction mixture was stirred continuously for 1 hour. Subsequently, sodium cyanoborohydride (0.7 g, 12 mmol) was added to the reaction mixture at 0 °C and stirring was continued for 16 h at room temperature. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm the completion of the reaction. Eventually, the target product N-methyltetrahydro-2H-pyran-4-amine (1 g) was isolated as a yellow liquid. Mass spectrum (ESI) m/z 115 [M]+. | | References | [1] Patent: US2016/289171, 2016, A1. Location in patent: Paragraph 1794
[2] Patent: US2017/348315, 2017, A1. Location in patent: Paragraph 0322 |
| | Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl Preparation Products And Raw materials |
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