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beta-Nicotinamide adenine dinucleotide disodium salt

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Company Name: Kono Chem Co., Ltd
Tel: +86-132 8924 6953(Whatsapp/Wechat)
Email: info@konochemical.com
Products Intro: Product Name:NADH
CAS:606-68-8
Purity:0.99 Package:1g;25g;1kg;25kg;100kg Remarks:Pharmaceutical grade
Company Name: Casorganics US Corp
Tel: +17326109938
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Products Intro: Product Name:beta-Nicotinamide adenine dinucleotide disodium salt
CAS:606-68-8
Purity:99.8% Package:1KG;USD|5KG;USD|25KG;USD
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-571-85586718
Email: sales@capotchem.com
Products Intro: Product Name:Nicotinamide adenine dinucleotide (reduced) disodium salt(NADH 2Na)
CAS:606-68-8
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
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Products Intro: Product Name:beta-Nicotinamide adenine dinucleotide disodium salt
CAS:606-68-8
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:beta-Nicotinamide adenine dinucleotide disodium salt
CAS:606-68-8
Purity:99% Package:500G;1KG;5KG;25KG

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beta-Nicotinamide adenine dinucleotide disodium salt Basic information
Product Name:beta-Nicotinamide adenine dinucleotide disodium salt
Synonyms:NADH,disodiumsalthydrate;beta-Nicotinamide adenine dinucleotide disodium salt:NADH;NADH DISODIUM SALT;NADH;N A D H, REDUCED FORM, DISODIUM;NADH-NA2;NICOTINAMIDE-ADENINE DINUCLEOTIDE (REDUCED) DISODIUM SALT;NICOTINAMIDE ADENINE DINUCLEOTIDE (REDUCED FORM) DISODIUM SALT
CAS:606-68-8
MF:C21H27N7Na2O14P2
MW:709.4
EINECS:210-123-3
Product Categories:Bioproducts;Cofactor;Cofactors and SubstratesBiochemicals and Reagents;NAD and AnalogsResearch Essentials;Nucleosides and NucleotidesEnzymes, Inhibitors, and Substrates;Oxidation-ReductionMetabolic Pathways;Core Bioreagents;Electron Transport and Cellular Respiration;Metabolic Pathways;Metabolites and Cofactors on the Metabolic Pathways Chart;TCA;Oxidation-Reduction;Cofactors;Enzymes, Inhibitors, and Substrates;Biochemicals and Reagents;NAD and Analogs;Nucleosides, Nucleotides, Oligonucleotides;nucleoside;Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Phosphorylating and Phosphitylating Agents
Mol File:606-68-8.mol
beta-Nicotinamide adenine dinucleotide disodium salt Structure
beta-Nicotinamide adenine dinucleotide disodium salt Chemical Properties
Melting point 140-142°C
storage temp. 2-8°C
solubility H2O: 50 mg/mL, clear to nearly clear, yellow
form Powder
color Yellow
PH7.5 (100mg/mL in water, ±0.5)
Water Solubility soluble
BRN 5230241
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyQRGNQKGQENGQSE-WUEGHLCSSA-L
CAS DataBase Reference606-68-8
EPA Substance Registry SystemReduced .beta.-nicotinamide adenine dinucleotide disodium salt (606-68-8)
Safety Information
Hazard Codes Xn
Risk Statements 23/24/25-36/37/38-39/23/24/25-40-22
Safety Statements 26-36/37/39-45-24/25-36/37
WGK Germany 3
3-10-23
TSCA Yes
HS Code 29349990
MSDS Information
beta-Nicotinamide adenine dinucleotide disodium salt Usage And Synthesis
Chemical Propertiesbeige powder
UsesOne of the biologically active forms of nicotinic acid. Serves as a coenzyme of hydrogenases and dehydrogenases. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen d onor in the respiratory chain. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. Occurs in 2 forms, α-NAD and β-NAD, distinguished by the configura tion of the ribosyl nicotinamide linkage. Only the β-anomer is bioactive.
DefinitionA dehydrogenase complex that is the reduced formof NAD.
Purification MethodsThis coenzyme is available in high purity, and it is advisable to buy a fresh preparation rather than to purify an old sample as purification will invariably lead to a more impure sample contaminated with the oxidised form (NAD). It has UV max at 340nm ( 6,200 M-1cm-1) at which wavelength the oxidised form NAD has no absorption. At 340nm a 0.161mM solution in a 1cm (pathlength) cell has an absorbance of 1.0 unit. The purity is best checked by the ratio A280nm/A340nm ~2.1, a value which increases as oxidation proceeds. The dry powder is stable indefinitely at -20o. Solutions in aqueous buffers at pH ~7 are stable for extended periods at -20o and for at least 8hours at 0o, but are oxidised more rapidly at 4o in a cold room (e.g. almost completely oxidised overnight at 4o). [UV: Drabkin J Biol Chem 175 563 1945, Fluorescence: Boyer & Thorell Acta Chem Scand 10 447 1956, Redox: Rodkey J Biol Chem 234 188 1959, Schlenk in The Enzymes 2 250, 268 1951, Kaplan in The Enzymes 3 105, 112 1960.] Deuterated NADH, i.e. NADD, has been purified through the anion exchange resin AG-1 x 8 (100-200 mesh, formate form) and through a Bio-Gel P-2 column. [Viola et al. Anal Biochem 96 334 1979, Beilstein 26 III/IV 3639.]
beta-Nicotinamide adenine dinucleotide disodium salt Preparation Products And Raw materials
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