ChemicalBook > Product Catalog >Biochemical Engineering >Enzymes And Coenzymes drugs >Collagenase

Collagenase

Collagenase Suppliers list
Company Name: Anhui Royal Chemical Co., Ltd.
Tel: +86-025-86655873
Email: marketing@royal-chem.com
Products Intro: Product Name:COLLAGENASE
CAS:9001-12-1
Purity:99.00% Package:100mg/branch Remarks:Biochemistry;Enzyme
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Email: linda@hubeijusheng.com
Products Intro: Product Name:Collagenase clostridium histolyticum
CAS:9001-12-1
Purity:99% Package:5KG;1KG
Company Name: Hebei Guanlang Biotechnology Co., Ltd.
Tel:
Email: sales3@crovellbio.com
Products Intro: Product Name:Collagenase
CAS:9001-12-1
Purity:99%
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-13650506873
Email: sales@chemdad.com
Products Intro: Product Name:Collagenase
CAS:9001-12-1
Purity:0.98 Package:1kg,2kg,5kg,10kg,25kg
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
Tel: +86 13343822234;+86 18703821685;+86 18530059196;+86 19139973225
Email: sales5@alfachem.cn;sales9@alfachem.cn;sale1@alfachem.cn;sales7@alfachem.cn
Products Intro: CAS:9001-12-1
Purity:97% Package:1g/25g/100g/500g/1kg/bulk package

Lastest Price from Collagenase manufacturers

  • Collagen Peptide
  • US $15.00 / KG
  • 2021-10-20
  • CAS:
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 9000kg/per week
  • Collagenase
  • US $0.00-0.00 / g
  • 2021-09-29
  • CAS:9001-12-1
  • Min. Order: 1g
  • Purity: 98.0%
  • Supply Ability: 1kg/month
  • Collagenase
  • US $19.00 / ASSAYS
  • 2021-07-08
  • CAS:9001-12-1
  • Min. Order: 100化验
  • Purity: 99%
  • Supply Ability: 100 mt
Collagenase Basic information
Description References
Product Name:Collagenase
Synonyms:COLLAGENASE TYPE X;Collagenase from Clostridium histolyticum;collagenase crude type ia cell culture*tested;collagenase F. clostridium histolyticum;collagenase from achromobacter iophagus;collagenase sterile filtered type vii-S;collagenase type I-S;Collagenase A
CAS:9001-12-1
MF:C60H100N2
MW:849.4494
EINECS:232-582-9
Product Categories:STREPTOKINASE;Biochemistry;Enzyme;Hydrolase
Mol File:9001-12-1.mol
Collagenase Structure
Collagenase Chemical Properties
storage temp. -20°C
solubility Soluble in aqueous buffers.
form powder
color light brown
PH7.0
Merck 2481
CAS DataBase Reference9001-12-1
EPA Substance Registry SystemCollagenase (9001-12-1)
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-42
Safety Statements 22-24-26-36/37
WGK Germany 1
10-21
HS Code 3507907000
MSDS Information
ProviderLanguage
Aspergillopeptidase C English
Collagenase Usage And Synthesis
DescriptionCollagenases are a category of enzymes that can digest native collagen, the major fibrous component of animal extracellular connective tissue. Collagenases can be produced by some bacterias such as Clostridium  and can also be made by the animal body as part of its normal immune response. They normally target the connective tissue in muscle cells and other body organs. They can break peptide bonds within collagen and help create collagen by cleaving pro-collagen, collagen's precursor, once it is secreted by the cell. Bacterial collagenases exhibit broader substrate specificity than animal collagenases and unlike animal collagenases that split collagen in its native triple-helical conformation, bacterial collagenase can degrade both water-insoluble native collagens and water-soluble denatured ones. In addition, bacterial collagenase can attack almost all collagen types, and is able to make multiple cleavages within triple helical regions.  Collagenases have a molecular weight ranging from 68 kilodaltons (kDa) to 130 Kda due to differing sizes based on the class to which the isolate belongs. The optimal pH for stability ranges from approximately 6.3 to 7.5 with a theoretical isoelectric point of 5.62. Numerous compounds and molecules have the capability of acting as collagenases activator or inhibitor. For example, Ca2+ and Zn2+ ions are two known activators. On the other hand, ethylenediaminetetraacetic acid (EDTA), ethylene glycol tetraacetic acid (EGTA), cysteine, histidine, dithiothreitol (DTT), 2-mercaptoethanol, o-phenanthroline, Hg2+, Pb2+, Cd2+, Cu2+, and Zn2+ are all known inhibitors of collagenase activity.
References1.https://en.wikipedia.org/wiki/Collagenase
2.http://www.wisegeek.com/what-is-collagenase.htm
3.http://www.rockland-inc.com/collagenase.aspx
4.http://www.worthington-biochem.com/cls/default.html
UsesThis collagenase has been tested with cell lines to verify the product is not cytotoxic. Collagenase is typically used to digest the connective components in tissue samples to liberate individual cells. The concentration for cartilage dispersal is 1-2 mg/ml, but literature searches should be performed for species specific and/or tissue specific concentrations.
UsesIn investigation of the structure and biosynthesis of collagen; in dispersion of cells for tissue culture studies.
DefinitionA rare proteinase that catalyzes the hydrolysis of collagen. Collagenase activity has been demonstrated in several venoms of crotalid and viperid snakes and it occurs in certain species of clostridium.
Purification MethodsCollagenase is purified by using N-ethylmaleimide to activate the enzyme, and wheat germ agglutinin-agarose affinity chromatography [Callaway et al. Biochemistry 25 4757 1986].
Collagenase Preparation Products And Raw materials
Tag:Collagenase(9001-12-1) Related Product Information
MMP-2(Collagenase IV /Gelatinase A/Metallo proteinase-2) TEV protease Basic protease 1 VIAL PROTEASE-INHIBITOR-MIX HP EC 3.4.21.19 TERT-BUTYL ISOCYANIDE COBALT ETHYLENE DIAMINE CHLORIDE METHYL ISOCYANOACETATE Ethyl isocyanoacetate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tosylmethyl isocyanide 2,4-PENTANEDIONE, SILVER DERIVATIVE N-BUTYLISOCYANIDE CLOSTRIDIUM PROTEASE Collagenase MarineCollagen PROTEASE