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Coumarin

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CAS:91-64-5
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
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CAS:91-64-5
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CAS:91-64-5
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Purity:99% Package:500G;1KG;5KG;25KG
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Products Intro: Product Name:Coumarin
CAS:91-64-5

Lastest Price from Coumarin manufacturers

  • Coumarin
  • US $1.00 / kg
  • 2019-04-01
  • CAS:91-64-5
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 100KG
Coumarin Basic information
Brief Introduction Chemical Properties Uses
Product Name:Coumarin
Synonyms:Coumarin solution;TIMTEC-BB SBB000094;O-HYDROXYCINNAMIC ACID LACTONE;TONKA BEAN CAMPHOR;5,6-BENZO-2-PYRONE;AKOS 212-75;2H-1-BENZOPYRAN-2-ONE;2H-1-BENZOPYAN-2-ONE
CAS:91-64-5
MF:C9H6O2
MW:146.14
EINECS:202-086-7
Product Categories:FINE Chemical & INTERMEDIATES;Food & Feed ADDITIVES;Coumarins;Coumarin;Natural Plant Extract;Aromatics;Inhibitors;Heterocycles;Pharmaceutical intermediates;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Fluorescent
Mol File:91-64-5.mol
Coumarin Structure
Coumarin Chemical Properties
Melting point 68-73 °C(lit.)
Boiling point 298 °C(lit.)
density 0.935
vapor pressure 0.01 mm Hg ( 47 °C)
refractive index 1.5100 (estimate)
Fp 162 °C
storage temp. Refrigerator
solubility 1.7g/l
form Crystals or Crystalline Powder
color White
PH RangeNon' uorescence (9.5) to light green ' uorescence (10.5)
Water Solubility 1.7 g/L (20 ºC)
λmax275nm
Merck 14,2562
BRN 383644
Major Applicationcolor filter, organic electroluminescent devices, liquid crystal displays, field emission displays, inks, nickel plating, detergents, deodorant for shoes, petroleum products, cigarettes, personal care products, cosmetics, sunscreen cream, perfumes, nucleic acid sequencing, antiinflammatory agent, treatment of cancer, neurotransmission disorders, bleeding disorders, cerebrovascular disease, thrombosis, hemorrhoids, rheumatic disease, arthritic disease, epilepsy, vaginitis, painkiller, teeth whitening agent, skin whitening agent, wound healing promoter
InChIKeyZYGHJZDHTFUPRJ-UHFFFAOYSA-N
CAS DataBase Reference91-64-5(CAS DataBase Reference)
NIST Chemistry ReferenceCoumarin(91-64-5)
EPA Substance Registry System2H-1-Benzopyran- 2-one(91-64-5)
Safety Information
Hazard Codes Xn
Risk Statements 22-40-36/37/38-20/21/22-43
Safety Statements 36-36/37-26
RIDADR UN 2811 6.1/PG 3
WGK Germany 1
RTECS GN4200000
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29322010
Hazardous Substances Data91-64-5(Hazardous Substances Data)
ToxicityLD50 orally in rats, guinea pigs: 680, 202 mg/kg (Jenner)
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Coumarin Usage And Synthesis
Brief Introduction
It is also known as 1, 2-benzopyrone, cis ortho-caberillin, o-hydroxy cinnamon lactone and coumarin. It is contained in many natural plants in the form of glycosides and esters as vanillin instead of free-form. Coumarin will come out when certain plants are fermented and processed. Coumarin is found in the seeds of Dayton beans (Riccinechoides) in 1820 and is widely distributed in the plant kingdom, especially in plant species including Umbelliferae, Soybean, Rutaceae and Calyx. Seeds contain about 1.5% of the coumarin. In addition, coumarin is also contained in lavender oil, cinnamon oil and Peru balsam. Coumarin is spicy with sweet and lemongrass aroma. The aroma is emitted from the pink gum in the leaves of the fragrant beans, and the gum is made from the breakdown of the coumarin glycosides in the leaves. The aroma emitted by Sweet alfalfa is actually from the release of coumarin due to fermentation and decomposition during the stacking process. Precipitate from the ether appears as orthorhombic white pyramid or oblique sheet-like crystals with Lemongrass-type smell. It can subject to sublimation.
Chemical PropertiesGolden crystalline solid (fronds or rhomboid); it is sweet with black beans-like aroma, dried herbs aroma and fennel aroma. After dilution, it smells like dried straw, nuts and tobacco. It is insoluble in cold water but soluble in hot water, ethanol and chloroform, easily soluble in ether and benzene. The solubility in 100ml of water at 25 ℃ is only 0.01g; 13 7g in 100ml of ethanol at 16 ℃; 1g in 50 mL 100℃ hot water. Oral LD50: 680mg / kg for rat.
Usesused as a spice for the preparation of floral fragrances such as lavender, rosemary and rosemary, used in perfumes, cosmetics, soaps and detergents; used as flavoring agents for blending fragrances to make the aroma be lasting and unchanged; used as an electroplating additive to prevent the occurrence of pores in coating and can increase the brightness; as the flavor enhancer of printing ink and plastic; formerly used as spices and cigarettes spices, banned from 197; Since then, China had also prohibited it application in food; used as pharmaceutical raw materials.
Coumarin, as a laser dye, has an output laser range be within the blue-green region (420 ~ 570nm), has high fluorescence quantum efficiency, such as 7-ethylamino-6-methyl-4-trifluoromethyl coumarin Lactone 307), the structure is as follows:
Chemical PropertiesWHITE CRYSTALS OR CRYSTALLINE POWDER
UsesPharmaceutic aid (flavor). Found in tonka beans, levender oil, woodruff, sweet clover.
Usesantineoplastic, antiinflammatory, antihyperglycaemic
Usescoumarin is considered a blood thinner, it can also increase blood flow. Some sources cite anti-oxidant capacities, as well. It is a specific plant constituent and is what creates the fragrance of freshly mowed hay. Coumarin is found in such plants as cherries, lavender, licorice, and sweet clover.
DefinitionA colorless crystalline compound with a pleasant odor, used in making perfumes. On hydrolysis with sodium hydroxide it forms coumarinic acid.
DefinitionChEBI: A chromenone having the keto group located at the 2-position.
General DescriptionColorless crystals, flakes or colorless to white powder with a pleasant fragrant vanilla odor and a bitter aromatic burning taste.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileCoumarin is sensitive to exposure to light. Coumarin is also sensitive to heat. Coumarin is incompatible with strong acids, strong bases and oxidizers. Coumarin is hydrolyzed by hot concentrated alkalis. Coumarin can be halogenated, nitrated and hydrogenated (in the presence of catalysts).
HazardToxic by ingestion; carcinogenic. Use in food products prohibited (FDA). Questionable carcinogen.
Health HazardSYMPTOMS: Exposure to Coumarin may cause narcosis. It may also cause irritation and liver damage.
Fire HazardCoumarin is combustible.
Contact allergensCoumarin is an aromatic lactone naturally occurring in Tonka beans and other plants. As a fragrance allergen, it has to be mentioned by name in cosmetics within the EU
Safety ProfilePoison by ingestion, intraperitoneal, and subcutaneous routes. Questionable carcinogen with experimental tumorigenic data. Experimental teratogenic effects. Mutation data reported. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and fumes. See also KETONES and ANHYDRIDES.
Purification MethodsCoumarin crystallises from ethanol or water and sublimes in vacuo at 43o [Srinivasan & deLevie J Phys Chem 91 2904 1987]. [Beilstein 17/10 V 143.]
Tag:Coumarin(91-64-5) Related Product Information
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