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| | 2,3-Pyrazinecarboxylic anhydride Basic information |
| Product Name: | 2,3-Pyrazinecarboxylic anhydride | | Synonyms: | 2,3-PYRAZINECARBOXYLIC ANHYDRIDE;2,3-PYRAZINEDICARBOXLIC ANHYDRIDE;2,3-PYRAZINEDICARBOXYLICANHYDRATE;2,3-Pyrazinedicarboxylic acid anhydride;Furo[3,4-b]pyrazine-5,7-dione (9CI);5,7-Dihydrofuro[3,4-b]pyrazine-5,7-dione;Name: 2,3-Pyrazinedicarboxylic anhydride;furo[3,4-b]pyrazine-5,7-quinone | | CAS: | 4744-50-7 | | MF: | C6H2N2O3 | | MW: | 150.09 | | EINECS: | 225-260-4 | | Product Categories: | Pesticide intermediates;GLYCINESCAFFOLD;Fused Ring Systems;bc0001 | | Mol File: | 4744-50-7.mol |  |
| | 2,3-Pyrazinecarboxylic anhydride Chemical Properties |
| Melting point | 210 °C (dec.)(lit.) | | Boiling point | 357.3±22.0 °C(Predicted) | | density | 1.686±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Actonitrile (Slightly), DMSO | | form | Solid | | pka | -3.43±0.20(Predicted) | | color | White to light brown crystalline powder | | InChI | InChI=1S/C6H2N2O3/c9-5-3-4(6(10)11-5)8-2-1-7-3/h1-2H | | InChIKey | AWJWCTOOIBYHON-UHFFFAOYSA-N | | SMILES | C12C(=O)OC(=O)C1=NC=CN=2 | | LogP | -0.900 (est) | | CAS DataBase Reference | 4744-50-7(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29349990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2,3-Pyrazinecarboxylic anhydride Usage And Synthesis |
| Chemical Properties | Crystallizes. Melting point 223-224°C (decomposes at 210°C). | | Uses | 2,3-Pyrazinedicarboxylic Anhydride is a reagent used in the synthesis of highly potent and selective abietane type diterpenoid amides. | | Synthesis | Pyrazine-2,3-dicarboxylic acid (4.0 g, 23.8 mmol) was dissolved in acetic anhydride (30 mL).The reaction mixture was refluxed for one hour, and subsequently cooled down to 0 °C in ice bath.The obtained crystals of pyrazine-2,3-dicarboxylic anhydride were filtered off (yield 70%).
 | | References | [1] Molecules, 2017, vol. 22, # 9,
[2] Journal of the American Chemical Society, 1953, vol. 75, p. 679
[3] Helvetica Chimica Acta, 1958, vol. 41, p. 498,509 |
| | 2,3-Pyrazinecarboxylic anhydride Preparation Products And Raw materials |
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