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Cloquintocet-mexyl

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CAS:99607-70-2
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Cloquintocet-mexyl manufacturers

  • Cloquintocet-mexyl
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  • $30.00 / 1g
  • 2024-04-26
  • CAS:99607-70-2
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  • Purity: 98%
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  • 2023-11-22
  • CAS:99607-70-2
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  • Cloquintocet-mexyl
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  • $30.00 / 1KG
  • 2023-09-06
  • CAS:99607-70-2
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Cloquintocet-mexyl Basic information
Product Name:Cloquintocet-mexyl
Synonyms:heptan-2-yl 2-((5-chloroquinolin-8-yl)oxy)acetate;Cloquintocet-1;Cloquintocet-methyl;CLOQUINTOCET MEXYL TECHNICAL (SAFNER) BA;UPH-203 S CLOQUINTOCET MEXYL (SAFENER)"WE INTEND TO CLAIM REWARDS UNDER MERCHANDISE EXPORTS FROM INDIA SCHEME (MEIS)";CLOQUINTOCET-MEXYL;CLOQUINTOCET-1-METHYLHEXYL ESTER;CLOQUINTOCET-MEXYL PESTANAL, 250 MG
CAS:99607-70-2
MF:C18H22ClNO3
MW:335.83
EINECS:619-447-3
Product Categories:Alpha sort;C;CAlphabetic;CI - CL;Pesticides&Metabolites
Mol File:99607-70-2.mol
Cloquintocet-mexyl Structure
Cloquintocet-mexyl Chemical Properties
Melting point 69°
Boiling point 448.4±30.0 °C(Predicted)
density 1.163±0.06 g/cm3(Predicted)
vapor pressure 0-54.4Pa at 25-185.9℃
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
pka1.94±0.29(Predicted)
color White to Off-White
Merck 14,2401
Stability:Stable. Incompatible with strong oxidizing agents.
LogP5.2-5.24 at 25℃ and pH5-9.1
Surface tension56.8-57.2mN/m at 590μg/L and 20℃
Dissociation constant3.55 at 20℃
CAS DataBase Reference99607-70-2(CAS DataBase Reference)
EPA Substance Registry SystemCloquintocet-mexyl (99607-70-2)
Safety Information
Hazard Codes Xi
Risk Statements 43
Safety Statements 36/37
RIDADR UN 3077
WGK Germany 2
RTECS AG1265000
HS Code 2933.49.3000
ToxicityLD50 in rats (mg/kg): >2000 orally; >2000 dermally; LC50 (4 hr) in rats: >935 mg/m3 by inhalation (Amrein)
MSDS Information
Cloquintocet-mexyl Usage And Synthesis
DescriptionCloquintocet-mexyl is a colourless crystalline herbicide safener. It is categorized as Class III toxin.
Chemical Propertiesbeige solid
UsesCloquintocet-mexyl is used as a herbicide.
UsesCloquintocet-mexyl is a herbicide. It is used to control coarse annual grass of the family poaceae (gramineae). lt was developed by the swiss ciba geigy in the 1980s and the patent has expired.
DefinitionChEBI: Heptan-2-yl [(5-chloroquinolin-8-yl)oxy]acetate is a member of the class of quinolines that is quinoline which is substituted by a chloro group at position 5 and by a 2-[(heptan-2-yl)oxy]-2-oxoethoxy group at position 8. It is an aromatic ether, an organochlorine compound, a member of quinolines and a carboxylic ester.
Agricultural UsesCloquintocet-mexyl is a safener that can be used in conjunction with various herbicides to reduce phytotoxicity to crops. Though effective as a safener, the manufacture, storage, and use of cloquintocet-mexyl containing products can present challenges owing to its sensitivity to water and its low melting temperature (i.e., 61-69° C. for technical material). When products containing cloquintocet-mexyl are prepared, stored, or used in the presence of water, cloquin tocet-mexyl can undergo hydrolysis to form cloquintocet acid, and/or form a needle-shaped, crystalline hydrate that can, lead to clogged spray nozzles during spray applications and/or possibly increased levels of crop phytotoxicity.
CarcinogenicityIn accordance with the EPA Proposed EPA Weight-of-the-Evidence Categories, August 1999, the HIARC classified cloquintocet-mexyl as "not likely to be a human carcinogen." Carcinogenicity studies in rats and mice did not show increased incidence of spontaneous tumor formation. With negative mutagenic test battery, it is suggested that cloquintocet-mexyl (CGA 185072) is not likely to be a human carcinogen.
MetabolismMetabolism studies in rats indicated that approximately 40% of the administered dose of cloquintocet-mexyl was absorbed through the gastrointestinal tract and subsequently excreted via the urine. Fecal excretion accounted for approximately 60% of the administered dose. The chemical was rapidly eliminated (more than 80% of the administered dose) via feces and urine within 48 hours post-dosing. Sex, dosing regime, and dose levels had little effect on the excretion pattern. Excretion patterns were similar between the biliary cannulated and non-cannulated animals indicating that there was no enterohepatic circulation of the chemical. Three days after administration, tissue radioactivity accounted for less than 0.3% of the administered dose (or was non-detectable) and was not detectable in the expired air. At day three post-dosing, most tissue residues of radioactivity were below the limit of detection. The major metabolic pathway of cloquintocet-mexyl was ester hydrolysis to yield 5-chloro-8-quinolinoxy acetic acid, the major metabolite in the fecal and urinary pools.
Toxicity evaluationCloquintocet-mexyl has a low order of acute oral, dermal, and inhalation toxicity. It is slightly irritating to the eyes and non-irritating to the skin. Cloquintocet-mexyl is a skin sensitizer. The chemical is not genotoxic and is not a reproductive and developmental toxicant. There is no evidence of neurotoxicity in the available studies. Cloquintocet-mexyl is classified as “not likely to be a human carcinogen.” The main metabolite for cloquintocet-mexyl is 5-chloro-8-quin-linoxyacetic acid, and testing on the metabolite is part of the toxicology database for cloquintocet-mexyl.
Cloquintocet-mexyl Preparation Products And Raw materials
Tag:Cloquintocet-mexyl(99607-70-2) Related Product Information
Methyltriethoxysilane Isopropyl acetate Clioquinol Magnesium acetate Ethyl acetate Butyl acetate Ethyl methoxyacetate Sodium acetate Ethoxyquin Cloquintocet Methyltrimethoxysilane Methoxyacetic acid Vinyl acetate Ammonium acetate Benzyl acetate Cellulose acetate acetic acid, triethoxy-, ethyl ester 4-Methoxyphenylacetic acid