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MG-132

MG-132 Suppliers list
Company Name: Alpha Biopharmaceuticals Co., Ltd
Tel: 0086-411-39042497
Email: sales@alphabiopharm.com
Products Intro: Product Name:MG-132
CAS:133407-82-6
Purity:>98.5% Package:5g;25g;100g;250g;1kg;bulk Remarks:B0215
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: CAS:133407-82-6
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: Biochempartner
Tel: 0086-13720134139
Email: candy@biochempartner.com
Products Intro: Product Name:MG-132
CAS:133407-82-6
Purity:98% HPLC LCMS Package:10G;20G
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Email: linda@hubeijusheng.com
Products Intro: Product Name:MG-132
CAS:133407-82-6
Purity:0.99 Package:5KG;1KG
Company Name: BOC Sciences
Tel: 1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:MG-132
CAS:133407-82-6

MG-132 manufacturers

  • MG-132
  • $5.00 / KG
  • 2021-11-08
  • CAS:133407-82-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20 Tons
  • MG-132
  • $1.00 / g
  • 2019-12-20
  • CAS:133407-82-6
  • Min. Order: 1g
  • Purity: 99.99%
  • Supply Ability: 2tons
MG-132 Basic information
Product Name:MG-132
Synonyms:PROTEASOME INHIBITOR MG-132;N-[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL-N-[(1S)-1-FORMYL-3-METHYLBUTYL]-L-LEUCINAMIDE;N-CBZ-LEU-LEU-LEUCINAL;Z-LLL-CHO;Z-LL-CHO;Z-LEU-LEU-LEU-CHO;Z-LEU-LEU-LEU-H;Z-LEU-LEU-LEU-H (ALDEHYDE)
CAS:133407-82-6
MF:C26H41N3O5
MW:475.62
EINECS:
Product Categories:API;peptides;Aldehydes;and Substrates;Application Index;inhibitor;Bioactive Small Molecules;Biochemicals and Reagents;Building Blocks;C13-C60;Calpain and Lysosomal Proteases;Calpain and Proteasome Inhibitors;Carbonyl Compounds;Cell Biology;Cytokine signaling;Apoptosis Inducers;Cell Signaling and Neuroscience;Cell Signaling Enzymes;Chemical Synthesis;Enzymes;Inhibitors;Intracellular Protein Degradation;Nitric Oxide and Cell Stress;Organic Building Blocks;Proteasome;Proteasomes;Z;ProteasomeInhibitors
Mol File:133407-82-6.mol
MG-132 Structure
MG-132 Chemical Properties
Melting point 80-84℃ (DEC.)
alpha -61~-67°
Boiling point 682.0±55.0 °C(Predicted)
density 1.073
Fp 366℃
storage temp. -20°C
solubility methanol: 1 mg/mL
form solid film
pka11.14±0.46(Predicted)
color White
Water Solubility Soluble in ethanol, chloroform, methanol, water.
InChIKeyTZYWCYJVHRLUCT-VABKMULXSA-N
Safety Information
Risk Statements 36/37/38
Safety Statements 24/25
WGK Germany 3
HS Code 29242990
MSDS Information
ProviderLanguage
SigmaAldrich English
MG-132 Usage And Synthesis
UsesA proteasome and NF-κB inhibitor.
DefinitionChEBI: A tripeptide that is L-leucyl-L-leucyl-L-leucine in which the C-terminal carboxy group has been reduced to the corresponding aldehyde and the N-terminal amino group is protected as its benzyloxycarbonyl derivative.
Biological ActivityPotent cell-permeable inhibitor of proteasome (IC 50 = 100 nM) and calpain (IC 50 = 1.2 μ M). Inhibits TNF- α -induced NF- κ B activation and I κ B α degradation. Induces neurite outgrowth in PC12 cells and has anticancer properties in vitro .
MG-132 Preparation Products And Raw materials
Tag:MG-132(133407-82-6) Related Product Information
MG-115 Trypsin ACHROMOPEPTIDASE trysin-chymotrypsin Basic protease ALLN LACTACYSTIN LEU-LEU-LEU CALPAIN INHIBITOR I CALPAIN INHIBITOR IV MG-132 in Solution 1 MG PROTEASOME INHIBITOR MG-132Z-LEU-LEU-LEU-H (ALDEHYDE) 5 MG PROTEASOME INHIBITOR MG-132Z-LEU-LEU-LEU-H (ALDEHYDE) PROTEASOME INHIBITOR MG-132Z-LEU-LEU-LEU-H (ALDEHYDE) Z-LLL-AMC Z-LEU-LEU-LEU-FMK MG-132 MG-262