- 4-Nitro-1-naphthol
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- $1000.00
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2026-02-02
- CAS:605-62-9
- Min. Order: 1KG
- Purity: 98%HPLC
- Supply Ability: 200tons
- 4-Nitro-1-naphthol
-
-
2025-04-04
- CAS:605-62-9
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
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| | 4-Nitro-1-naphthol Basic information |
| Product Name: | 4-Nitro-1-naphthol | | Synonyms: | 4-NITRO-1-NAPHTHOL;1-HYDROXY-4-NITRONAPHTHALENE;4-Nitro-1-naphthol,99%;4-Nitronaphthalen-1-ol;4-nitro-1-naphthalenol;1-Naphthalenol, 4-nitro-;4-Nitro-1-naphthol>;KAT8-IN-1 | | CAS: | 605-62-9 | | MF: | C10H7NO3 | | MW: | 189.17 | | EINECS: | 611-992-5 | | Product Categories: | | | Mol File: | 605-62-9.mol |  |
| | 4-Nitro-1-naphthol Chemical Properties |
| Melting point | 165-168°C | | Boiling point | 398.8±25.0 °C(Predicted) | | density | 1.413±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | powder to crystal | | pka | 6.22±0.40(Predicted) | | color | Light yellow to Brown | | BRN | 1959672 | | InChI | InChI=1S/C10H7NO3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6,12H | | InChIKey | AUIRNGLMBHIITH-UHFFFAOYSA-N | | SMILES | C1(O)=C2C(C=CC=C2)=C([N+]([O-])=O)C=C1 | | CAS DataBase Reference | 605-62-9(CAS DataBase Reference) |
| Provider | Language |
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ALFA
| English |
| | 4-Nitro-1-naphthol Usage And Synthesis |
| Uses | KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 μM (KAT8), 221 μM (KAT2B), 106 μM (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases[1]. | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 30, p. 906, 1987 DOI: 10.1021/jm00388a027 | | References | [1] Wapenaar H, et al. The relevance of Kicalculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor. Eur J Med Chem. 2017 Aug 18;136:480-486. DOI:10.1016/j.ejmech.2017.05.015 |
| | 4-Nitro-1-naphthol Preparation Products And Raw materials |
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