- Cyclooctanone
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2025-04-04
- CAS:502-49-8
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
- Cyclooctanone
-
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2022-02-19
- CAS:502-49-8
- Min. Order: 1KG
- Purity: 97.3%
- Supply Ability: 100 tons
- Cyclooctanone
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- $15.00
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2021-07-02
- CAS:502-49-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
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| | Cyclooctanone Basic information |
| | Cyclooctanone Chemical Properties |
| Melting point | 32-41 °C (lit.) | | Boiling point | 195-197 °C (lit.) | | density | 0.958 g/mL at 25 °C (lit.) | | refractive index | 1.4694 | | Fp | 163 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | 15g/l | | form | Crystalline Low Melting Solid | | color | Colorless to white | | PH | 7 (15g/l, H2O, 20℃) | | Water Solubility | Soluble in water at 20°C 15g/L. Soluble in acetone, alcohol, chloroform, methanol and benzene. | | BRN | 1280738 | | InChI | 1S/C8H14O/c9-8-6-4-2-1-3-5-7-8/h1-7H2 | | InChIKey | IIRFCWANHMSDCG-UHFFFAOYSA-N | | SMILES | O=C1CCCCCCC1 | | LogP | 2.11 | | CAS DataBase Reference | 502-49-8(CAS DataBase Reference) | | EPA Substance Registry System | Cyclooctanone (502-49-8) |
| Hazard Codes | C,Xi | | Risk Statements | 34-52/53-36/37/38 | | Safety Statements | 45-36/37/39-26-61 | | RIDADR | 1759 | | WGK Germany | 3 | | RTECS | GX9800000 | | TSCA | TSCA listed | | HazardClass | 8 | | HS Code | 29142990 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Eye Dam. 1
Skin Corr. 1B |
| | Cyclooctanone Usage And Synthesis |
| Chemical Properties | colorless to white crystalline low melting solid | | Uses | Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level. It is also used in the synthesis of 14-membered lactones. | | Synthesis Reference(s) | Journal of the American Chemical Society, 92, p. 5276, 1970 DOI: 10.1021/ja00720a078
The Journal of Organic Chemistry, 49, p. 3912, 1984 DOI: 10.1021/jo00195a007
Tetrahedron Letters, 36, p. 2921, 1995 DOI: 10.1016/0040-4039(95)00467-Q | | Purification Methods | Purify the ketone by sublimation after drying with Linde type 13X molecular sieves. The semicarbazone has m 168-169o (from dioxane) [Kohler et al. J Am Chem Soc 61 1060 1939]. The oxime has m 36-37o after subliming at high vacuum or distillation and has b 128-129o /14mm. The iso-oxime has m 72-73o [Ruzicka et al. Helv Chim Acta 32 548 1949]. [Beilstein 7 III 77, 7 IV 49.] |
| | Cyclooctanone Preparation Products And Raw materials |
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