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(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

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Company Name: Changzhou Rokechem Technology Co., Ltd.
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Products Intro: Product Name:(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
CAS:870281-86-0
Purity:99%min Package:1kg;USD
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
CAS:870281-86-0
Purity:98% Min. Package:1G;1KG;100KG
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
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Products Intro: Product Name:(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
CAS:870281-86-0
Purity:99% Package:100g ;1KG ;5KG 25KG
Company Name: Fluoropharm Co., Ltd.
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Products Intro: Product Name:(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
CAS:870281-86-0
Purity:0.98 Package:25KG;5KG;1KG Remarks:Mature product
Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: CAS:870281-86-0
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one manufacturers
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Basic information
Product Name:(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
Synonyms:(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone;Idelalisib INT;CAL-101 (N-1) Intermediate;(S)-2-(1-((9H-purin-6-yl-2,8-d2)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;CAL10;IdelalisibIntermediates 1;2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-3,4-dihydroquinazolin-4-one
CAS:870281-86-0
MF:C17H16FN3O
MW:297.33
EINECS:
Product Categories:intermediate;intermediates
Mol File:870281-86-0.mol
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Structure
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Chemical Properties
Boiling point 455.3±55.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
form Solid
pka8.23±0.29(Predicted)
color Off-White
Safety Information
MSDS Information
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Usage And Synthesis
Uses2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step.
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Preparation Products And Raw materials
Raw materials(S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate
Preparation ProductsCAL-101
Tag:(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one(870281-86-0) Related Product Information
Idelalisib Impurity 8 2-aMino-6-fluoro-N-phenylbenzaMide hydrochloride 2-Amino-6-fluorobenzoic acid BOC-ABU-OH (S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate CAL-101 2-Fluoro-6-nitro-N-phenylbenzamide