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| | PHENYL-P-BENZOQUINONE Basic information |
| Product Name: | PHENYL-P-BENZOQUINONE | | Synonyms: | 2-Phenyl-[1,4]benzoquinone;2-Phenyl-1,4-benzoquinone;2-phenyl-2,5-cyclohexadiene-1,4-dione;2-Phenylbenzoquinone;2-phenyl-p-benzoquinon;4-dione,2-phenyl-5-cyclohexadiene-1;o-phenylbenzoquinone;p-Benzoquinone, 2-phenyl- | | CAS: | 363-03-1 | | MF: | C12H8O2 | | MW: | 184.19 | | EINECS: | 206-654-5 | | Product Categories: | | | Mol File: | 363-03-1.mol |  |
| | PHENYL-P-BENZOQUINONE Chemical Properties |
| Melting point | 111-115 °C | | Boiling point | 278.14°C (rough estimate) | | density | 1.1336 (rough estimate) | | refractive index | 1.6086 (estimate) | | storage temp. | 2-8°C | | form | Chunks and Powder | | color | Yellow-brown | | EPA Substance Registry System | 2,5-Cyclohexadiene-1,4-dione, 2-phenyl- (363-03-1) |
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ACROS
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| | PHENYL-P-BENZOQUINONE Usage And Synthesis |
| Chemical Properties | Yellow-brown chunks and powder | | Uses | Phenylquinone is used for small molecule-based targeting of TTD-A dimerization to control TFIIH transcriptional activity whichrepresents a potential strategy for anticancer therapy. | | Synthesis Reference(s) | Journal of the American Chemical Society, 118, p. 2509, 1996 DOI: 10.1021/ja954009q | | Safety Profile | Poison by intraperitoneal route. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes | | Purification Methods | Crystallise the quinone from heptane, pet ether (b 60-70o), *C6H6 (m 113.5-114.5o) or EtOH (m 112-113o) and sublime it in vacuo. [Carlson & Miller J Am Chem Soc 107 479 1985, Beilstein 7 H 740, 7 III 3764.] |
| | PHENYL-P-BENZOQUINONE Preparation Products And Raw materials |
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