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| | URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Basic information |
| | URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: soluble100 mg/mL, clear, colorless to very faintly yellow | | form | Powder | | color | White | | Water Solubility | Soluble in water to 100mM | | Stability: | Hygroscopic |
| | URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Usage And Synthesis |
| Description | Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52 for human P2Y6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis. | | Uses | Uridine 5''-Diphosphate Sodium Salt is a potentially useful P2Y receptor agonist. It can be used in biological study and use in chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination. | | Uses | A phosphorylated derivative of the nucleoside Uridine. It is further phosphorylated by nucleoside diphosphokinase to form the triphosphate analogue. | | Biochem/physiol Actions | P2Y receptor agonist. | | in vitro | Uridine-5'-diphosphate disodium salt (100 μM; for 15 min) significantly induces microglial CCL2 and CCL3 mRNA expression. |
| | URIDINE 5'-DIPHOSPHORIC ACID SODIUM SALT Preparation Products And Raw materials |
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