ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >aliphatic ketones >(S)-(-)-LIMONENE


(S)-(-)-LIMONENE Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-66670886
Products Intro: Product Name:(S)-(-)-LIMONENE
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: Product Name:5989-54-8
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Nanjing ChemLin Chemical Industry Co., Ltd.
Tel: 025-83697070;
Products Intro: CAS:5989-54-8
Purity:98% Package:g-Kg Remarks:Colorless liquid
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Products Intro: Product Name:(S)-(-)-Limonene
Purity:GC>=98% Package:100mg
Tel: 86-18523575427
Products Intro: Product Name:(-)-limonene
Purity:0.99 Package:1kg

Lastest Price from (S)-(-)-LIMONENE manufacturers

  • (S)-(-)-Limonene 96%
  • US $15.00-10.00 / KG
  • 2021-07-02
  • CAS:5989-54-8
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
(S)-(-)-LIMONENE Basic information
Description Chemical Composition and Reactions Application Safety and Side Effects Dosing
Product Name:(S)-(-)-LIMONENE
Synonyms:(-)-1,8-p-menthadiene,(S)-(-)-limonene;(S)-(-)-1-methyl-4-(1-methylethenyl)cyclohexene;(s)-(-)-p-mentha-1,8-diene;(s)-(-)-p-mentha-8-diene;(s)-1-methyl-4-(1-methylethenyl)cyclohexene;beta-limonene;cyclohexene,1-methyl-4-(1-methylethenyl)-,(S)-;p-Mentha-1,8-diene, (S)-(-)-
Product Categories:Biochemistry;Monocyclic Monoterpenes;Terpenes
Mol File:5989-54-8.mol
(S)-(-)-LIMONENE Structure
(S)-(-)-LIMONENE Chemical Properties
Melting point -74°C
alpha -99.5 º (C=NEAT)
Boiling point 175-177 °C(lit.)
density 0.844 g/mL at 25 °C(lit.)
vapor density 4.7 (vs air)
vapor pressure <3 mm Hg ( 14.4 °C)
refractive index n20/D 1.471(lit.)
Fp 119 °F
storage temp. Sealed in dry,Store in freezer, under -20°C
form Liquid
color Clear colorless to pale yellow
optical activity[α]20/D 94±4°, c = 10% in ethanol
explosive limit0.7-6.1%(V)
Water Solubility Insoluble
Merck 14,5493
BRN 2323991
Stability:Stable. Incompatible with strong oxidizing agents. Flammable.
CAS DataBase Reference5989-54-8(CAS DataBase Reference)
NIST Chemistry ReferenceCyclohexene, 1-methyl-4-(1-methylethenyl)-, (S)-(5989-54-8)
EPA Substance Registry SystemCyclohexene, 1-methyl-4-(1-methylethenyl)-, (4S)- (5989-54-8)
Safety Information
Hazard Codes Xi,N
Risk Statements 10-38-43-50/53
Safety Statements 24-37-60-61
RIDADR UN 2052 3/PG 3
WGK Germany 2
RTECS OS8350000
HazardClass 3
PackingGroup III
HS Code 29029090
MSDS Information
ACROS English
SigmaAldrich English
ALFA English
(S)-(-)-LIMONENE Usage And Synthesis
Description(S)-(-)-Limonene is one of the most popular natural occurring cyclic terpenes and its chemical name is D-Limonene. It is a colorless liquid at room temperature with a characteristic lemon-like odor. Although it is insoluble in ether and alcohol, (S)-(-)-Limonene is soluble in water and has a boiling point of 74oC. (S)-(-)-Limonene can be recovered from orange peel from the conversion of press liquor to molasses. It is a major constituent of numerous citrus oils such as lemon, orange, lime, mandarin, and grapefruit, which are fruits from the Rutaceae family.
(S)-(-)-Limonene can be obtained by stream distillation of pulp and citrus peels resulting from production of cold-pressed oils and juice or from deterpenation of citrus oils. The compound also occurs in other essences and oils obtained during the processing of citrus juice, including deoiler, essence oil, aroma, and juice oil.
Chemical Composition and ReactionsThe main D-Limonene’s compositions include camphene, a-pinene, a-terpene, b-pinene, b-bisabolene, trans-a-bergamotene, limonene, neral, and nerol. It chemically belongs to the family of cycloalkane known as terpenes. Notably, its IUPAC name is 4-isopropeny–1–methylcyclohexane.
D-limonene can be distilled without decomposing and is a typically stable monoterpene, but can crack in high temperatures to form isoprene. D-limonene oxidizes easily in moist air to generate limonene oxide, carvone, and carveol. It dehydrates when reacted with Sulphur to form p-cymene. D-limonene isomerizes to conjugated diene α-terpinene when heated with mineral acid.
ApplicationClinical Applications
As an excellent cholesterol solvent, (S)-(-)-Limonene is normally used clinically to dissolve cholesterol containing gallstones.
It has also been used for relieving of heartburn and gastroesophageal reflux disorder (GERD) due to its gastric acid neutralizing characteristic and its support for normal peristalsis.
Studies have established (S)-(-)-Limonene’s chemo-preventive activity against many types of cancers. Patients with breast cancer showed partial response while patients with colorectal cancer were stable for more than six months from phase 1 clinical trials.
D-limonene is also used in maintaining regular bowel movements, particularly when slow movements are caused by a fungus known as Candida albicans that normally lead cause intestinal infection.
D-limonene is used as a mild suppressor of appetite, thus it can be employed to help in managing weight. Notably, it is useful when an individual has unhealthy blood sugar levels.
Personal Use
D-limonene is used as flavoring agent to mask the bitter taste of alkaloids as well as a fragrance in perfumery. The compound is also used in bath products, aftershave lotions as well as other personal products. It is normally added to cleaning products, for instance, hand wash solutions to give an orange or lemon fragrance.
Food Industry
D-limonene is used as a fragrance and flavoring in the manufacture of foods, chewing gums, and beverages.
Agricultural Use
D-limonene is utilized as botanical insecticide as well as in the organic herbicide “Aenger.”
Industrial Purposes
Since it is produced from naturally from citrus oil and byproducts during manufacturing of orange juice, d-Limonene is used as solvent for cleaning purposes, for example, the removal of oil from parts of machines.
It is also used as a paint stripper as well as an alternative fragrance to turpentine. In some airplane models, d-Limonene is used as a solvent in glues and as a constituent in some paints. The compound is also used in commercial air fresheners. It is also used to remove self-adhesive postage stamps from envelopes by philatelists.
d-Limonene has been considered as a biofuel due to its combustibility.
D-Limonene is used as a solvent for filament that is used in 3D printing. Printers are able to erect binders and supports from HIPS, which is a polystyrene plastic that can easily dissolve in d-Limonene.
The therapeutic properties of d-limonene include antimicrobial, antianaemic, antiseptic, and anti-sclerotic. The compound also has carminative, bactericidal, depurative, cicatrizant, diuretic, rubefacient, hyposensitive, vermifuge, and tonic characteristics.
D-Limonene is often used in preparing tissues (especially when cleaning dehydrated specimen) for histology due to its less toxic characteristic as compared to xylene.
D-limonene is used on wounds and sores, aromatherapy, douching, cataract, foots, mouth ulcers, varicose, and spots.
Safety and Side EffectsD-limonene is considered to have low toxicity; therefore, does not pose a carcinogenic, mutagenic, or nephrotoxic risk to humans. In proportional food amounts, d-limonene is safe. When taken orally for up to one year in correct medical amounts, d-limonene appears safe for most people.
However, there is no enough information or research regarding the effect of d-limonene on pregnant and breast feeding women when taken in larger medical amounts. As such, it is vital to stay on the safer side until more research is done.
DosingThe correct dosage for d-limonene is dependent on numerous factors, such as user’s health, age, as well as other conditions. It is important to note that natural products are not necessarily safe, thus dosage can be important.
Descriptionι-Limonene has a pleasant, lemon-like odor free from camphora ceous and turpentine-like notes. The most important and wide spread terpene; it is known in the d- and ι- optically active forms and in the optically inactive dl-form (known as dipentene); it has been reported found in more than 300 essential oils in amounts ranging from 90 - 95% (lemon, orange, mandarin) to as low as 1% (palmarosa);1 the most widespread form is the d-limonene, followed by the racemic form, and then ι-limonene.
Chemical Propertiesd-, l- or dl-Limonene has a pleasant, lemon-like odor free from camphoraceous and turpentine-like notes. Limonene is the most important and widespread terpene; it is known in the d- and l- optically active forms and in the optically inactive dl-form (known as dipentene).
Chemical Propertiescolourless liquid with lemon odour
OccurrenceIt has been reported found in more than 300 essential oils in amounts ranging from 90 to 95% (lemon, orange, mandarin) to as low as 1% (palmarosa); the most widespread form is the d-limonene, followed by the racemic form and then l-limo nene. Also reported found in ginger, nutmeg, pepper, mace, hop oil, coriander seed, calamus, dill herb, caraway seed and rosemary.
Preparationd-Limonene may be obtained by steam distillation of citrus peels and pulp resulting from the production of juice and cold pressed oils, or from deterpenation of citrus oils; it is sometimes redistilled.
DefinitionChEBI: An optically active form of limonene having (4S)-configuration.
Aroma threshold valuesDetection: 4 to 229 ppb
Taste threshold valuesTaste characteristics at 30 ppm: sweet, orange, citrus and terpy.
Contact allergensLimonene is a racemic form of dand l-limonene. d-Limonene is contained in Citrus species such as citrus, orange, mandarin, and bergamot. l-Limonene is contained in Pinus pinea.
Safety ProfileA skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Tag:(S)-(-)-LIMONENE(5989-54-8) Related Product Information
SPOROGEN RARECHEM AQ BC 9054 beta-Cadinene DIHYDRO CUMINYL ACETATE RARECHEM AQ BC 9096 RARECHEM AQ BC 9100 RARECHEM AL BZ 0002 (-)-PERILLALDEHYDE RARECHEM AQ BC 9102 Abn-cbd RARECHEM AQ BC 9104 RARECHEM AQ BC 9103 Muzigadial PERILLIC ACID (1R,3R,4R,4aR,6R)-4,4a-dimethyl-6-prop-1-en-2-yl-2,3,4,5,6,7-hexahydro-1H-naphthalene-1,3-diol RARECHEM AQ BC 9105 RARECHEM AQ BC 9098 (-)-CARVEOL