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| | 15-Keto prostaglandin f1alpha Basic information |
| Product Name: | 15-Keto prostaglandin f1alpha | | Synonyms: | 9ALPHA,11ALPHA-DIHYDROXY-15-OXO-PROST-13E-EN-1-OIC ACID;Prost-13-en-1-oic acid, 9,11-dihydroxy-15-oxo-, (9α,11α,13E)-;15-keto Prostaglandin F1α;15-keto Prostaglandin F1α MaxSpec? Standard;15-Keto prostaglandin f1alpha | | CAS: | 21562-58-3 | | MF: | C20H34O5 | | MW: | 354.48 | | EINECS: | | | Product Categories: | | | Mol File: | 21562-58-3.mol |  |
| | 15-Keto prostaglandin f1alpha Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >75 mg/ml; PBS (pH 7.2): >2 mg/ml |
| | 15-Keto prostaglandin f1alpha Usage And Synthesis |
| Description | 15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins. | | Uses | 15-keto Prostaglandin F1α (15-keto PGF1α) is a prostaglandin F1α metabolite. 15-keto Prostaglandin F1α (15-keto PGF1α) is an effective substrate for PGR-2. 15-keto Prostaglandin F1α (15-keto PGF1α) can be used to study physiological processes such as prostaglandin metabolism and lipogenesis[1]. | | References | [1] Chou WL, et al. Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of peroxisome proliferator-activated receptor gamma activation. J Biol Chem. 2007 Jun 22;282(25):18162-18172. DOI:10.1074/jbc.M702289200 |
| | 15-Keto prostaglandin f1alpha Preparation Products And Raw materials |
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