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| | 2-METHYL-1,3-BENZOXAZOLE-5-CARBOXYLIC ACID Basic information |
| Product Name: | 2-METHYL-1,3-BENZOXAZOLE-5-CARBOXYLIC ACID | | Synonyms: | 2-METHYL-1,3-BENZOXAZOLE-5-CARBOXYLIC ACID;2-METHYL-BENZOOXAZOLE-5-CARBOXYLIC ACID;OTAVA-BB 1136981;2-Methylbenzo[d]oxazole-5-carboxylic acid;2-Methyl-5-Benzoxazolecarboxylic acid;5-Benzoxazolecarboxylic acid, 2-Methyl-;2-Methylbenzoxazole-5-carboxylic Acid;2-Methyl-benzooxazole-6-carboxylic acid | | CAS: | 90322-32-0 | | MF: | C9H7NO3 | | MW: | 177.16 | | EINECS: | | | Product Categories: | | | Mol File: | 90322-32-0.mol |  |
| | 2-METHYL-1,3-BENZOXAZOLE-5-CARBOXYLIC ACID Chemical Properties |
| Melting point | 186-188℃ | | Boiling point | 353.5±15.0 °C(Predicted) | | density | 1.38 | | storage temp. | Sealed in dry,Room Temperature | | pka | 3.53±0.30(Predicted) | | Appearance | Light brown to off-white Solid |
| | 2-METHYL-1,3-BENZOXAZOLE-5-CARBOXYLIC ACID Usage And Synthesis |
| Synthesis | ). The reaction mixture was stirred at 25 °C for 3 hours. Upon completion of the reaction, the mixture was acidified to pH < 7 with dilute hydrochloric acid and a white solid was precipitated. The solid product was collected by filtration, washed with deionized water and subsequently dried under vacuum. Finally, the crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=1:1, v/v) to afford the target compound 2-methyl-5-benzoxazolecarboxylic acid (0.30 g, 65% yield) as a white solid. | | References | [1] Patent: WO2016/100184, 2016, A1. Location in patent: Paragraph 00321-00322 |
| | 2-METHYL-1,3-BENZOXAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials |
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