SGI-110 manufacturers
- Guadecitabine
-
- $0.00 / 25mg
-
2025-10-27
- CAS:929901-49-5
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | SGI-110 Basic information |
| Product Name: | SGI-110 | | Synonyms: | SGI-110;2'-Deoxy-5-azacytidylyl-(3'-5')-2'-deoxyguanosine;Guadecitabine;SGI110;SGI 110;CS-1302;Guanosine, 2'-deoxy-5-azacytidylyl-(3'→5')-2'-deoxy-;SGI-110 ammonium salt;SGI-110 Guadecitabine | | CAS: | 929901-49-5 | | MF: | C18H24N9O10P | | MW: | 557.41 | | EINECS: | | | Product Categories: | | | Mol File: | 929901-49-5.mol |  |
| | SGI-110 Chemical Properties |
| Boiling point | 956.4±75.0 °C(Predicted) | | density | 2.24±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C,unstable in solution, ready to use. | | solubility | H2O | | form | Powder | | pka | 1.37±0.50(Predicted) | | color | White to off-white |
| | SGI-110 Usage And Synthesis |
| Uses | SGI 110, is a DNA methyltransferases (DNMT) inhibitor. | | in vivo | Guadecitabine (S110) is effective at retarding tumor growth. While the tumors do not shrink in size with Guadecitabine treatment, they experience very minimal growth while the tumors treated with PBS only show substantial growth. In addition, Guadecitabine induces much less toxicity as determined by mouse weight changes when given subcutaneously (SQ) compare to that with IP injections[3]. | | target | DNA Methyltransferase | | IC 50 | DNA Methyltransferase |
| | SGI-110 Preparation Products And Raw materials |
|