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Amatek Scientific Co. Ltd.
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| Products Intro: |
Product Name:Phenyl-3-pyrrolidinyl-Methanone HCl
CAS:25503-87-1
Purity:97% HPLC Package:5g;25g;100g
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| | Phenyl-3-pyrrolidinyl-Methanone HCl Basic information |
| Product Name: | Phenyl-3-pyrrolidinyl-Methanone HCl | | Synonyms: | Phenyl(pyrrolidin-3-yl);PHENYL(PYRROLIDIN-3-YL)METHANONE HYDROCHLRIDE;Phenyl-3-pyrrolidinyl-Methanone HCl;3-benzoylpyrrolidine hydrochloride;Phenyl(3-pyrrolidinyl)methanone hydrochloride (1:1) | | CAS: | 25503-87-1 | | MF: | C11H14ClNO | | MW: | 211.68796 | | EINECS: | | | Product Categories: | | | Mol File: | 25503-87-1.mol |  |
| | Phenyl-3-pyrrolidinyl-Methanone HCl Chemical Properties |
| storage temp. | Sealed in dry,Room Temperature |
| | Phenyl-3-pyrrolidinyl-Methanone HCl Usage And Synthesis |
| Synthesis | General procedure for the synthesis of phenyl(pyrrol-3-yl)methanone hydrochloride from tert-butyl 3-benzoylpyrrolidine-1-carboxylate: Trifluoroacetic acid (10 mL) was added to a solution of tert-butyl 3-benzoylpyrrolidine-1-carboxylate (0.600 g, 2.18 mmol) in dichloromethane (40 mL), and the reaction mixture was stirred for 1 hour at room temperature. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure to give a residue. This residue was dissolved in methanol (10 mL), followed by the addition of a solution of 1 M hydrochloric acid in ether (100 mL). The resulting slurry was stirred at room temperature for 1 h and then concentrated to dryness under reduced pressure to give phenyl(pyrrolidin-3-yl)methanone hydrochloride (0.435 g, 94% yield) as a tan solid. The mass spectrum (APCI positive ion mode) showed m/z 176 (100%) [M+H]+. | | References | [1] Patent: WO2008/11130, 2008, A2. Location in patent: Page/Page column 147; 149 |
| | Phenyl-3-pyrrolidinyl-Methanone HCl Preparation Products And Raw materials |
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