- 2-Bromo-6-methylpyridine
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- $0.00 / 25Kg/Drum
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2026-04-30
- CAS:5315-25-3
- Min. Order: 1KG
- Purity: 98%min GC
- Supply Ability: 1000kg
- Yttrium oxide
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- $0.00 / 25KG
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2026-03-20
- CAS:1314-36-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
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| | 2-Bromo-6-methylpyridine Basic information |
| | 2-Bromo-6-methylpyridine Chemical Properties |
| Boiling point | 102-103 °C/20 mmHg (lit.) | | density | 1.512 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.562(lit.) | | Fp | 207 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform, Ethyl Aceate | | form | Liquid | | pka | 1.51±0.10(Predicted) | | Specific Gravity | 1.512 | | color | Clear colorless to yellow | | Water Solubility | Soluble in chloroform, ethyl aceate. Not miscible or difficult to mix with water. | | BRN | 107322 | | InChI | InChI=1S/C6H6BrN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3 | | InChIKey | SOHDPICLICFSOP-UHFFFAOYSA-N | | SMILES | C1(Br)=NC(C)=CC=C1 | | CAS DataBase Reference | 5315-25-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29333990 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2-Bromo-6-methylpyridine Usage And Synthesis |
| Chemical Properties | Light yellow liquid | | Uses | 2-Bromo-6-methylpyridine may be used in the synthesis of the following:
- 6,6′-dimethyl-2,2′-bipyridine
- 6-methyl-2-pyridyl-2-pyridylmethanone
- 2-methyl-6-(trimethylsilyl)-pyridine
- N,N′-bis-(6-methylpyrid-2-yl)-(1R,2R)-1,2- diaminocyclohexane (cydiampy)
- 2-methyl-6-(trimethylstannanyl)pyridine
- 2-(6-methylpyridin-2-yl)propan-2-ol
- bis[(2-bromo-6-methylpyridinium)hexafluorosilicate] monohydrate
| | Uses | 2-Bromo-6-methylpyridine is a halogenated pyridine derivative used is a building block in the preparation of nitrogen containing heterocyclic compounds. | | Synthesis Reference(s) | Journal of the American Chemical Society, 76, p. 3168, 1954 DOI: 10.1021/ja01641a017 | | General Description | 2-Bromo-6-methylpyridine is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported. | | Synthesis | The following are the steps for preparing 2-Bromo-6-methylpyridine:
Step 1: 2-Amino-6-methylpyridine With hydrogen bromide; bromine at -10~5℃ for 1.5h;
Step 2: With NaNO2 In water monomer at -10~5℃ for 1.5h;
Step 3: With sodium hydroxide In water monomer at -10℃. | | References | [1] Patent: CN105384684, 2016, A. Location in patent: Paragraph 0028; 0029
[2] Organic Letters, 2000, vol. 2, # 21, p. 3373 - 3376
[3] Phosphorus, Sulfur and Silicon and the Related Elements, 2002, vol. 177, # 11, p. 2579 - 2587
[4] Chemical and Pharmaceutical Bulletin, 1990, vol. 38, # 9, p. 2446 - 2458
[5] Journal of the Chemical Society - Perkin Transactions 1, 1998, # 19, p. 3151 - 3155 |
| | 2-Bromo-6-methylpyridine Preparation Products And Raw materials |
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