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| | 4,4'-propylenebis(piperazine-2,6-dione) Basic information |
| Product Name: | 4,4'-propylenebis(piperazine-2,6-dione) | | Synonyms: | 4,4'-propylenebis(piperazine-2,6-dione);4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione);RAZOXANUM;4,4'-(1-Methylethylene)bis(2,6-piperazinedione);4,4'-Propane-1,2-diyldipiperazine-2,6-dione;Propyliminum;4-[3-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;Troxozone | | CAS: | 21416-67-1 | | MF: | C11H16N4O4 | | MW: | 268.27 | | EINECS: | 244-379-2 | | Product Categories: | Angiogenesis and metastasis. | | Mol File: | 21416-67-1.mol |  |
| | 4,4'-propylenebis(piperazine-2,6-dione) Chemical Properties |
| Melting point | 237-239° | | Boiling point | 411.43°C (rough estimate) | | density | 1.2576 (rough estimate) | | refractive index | 1.6081 (estimate) | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO: soluble40mg/mL | | form | solid | | pka | 11.00±0.20(Predicted) | | color | White to off-white | | Water Solubility | 3g/L(25 ºC) |
| WGK Germany | 3 | | RTECS | TL6389900 |
| | 4,4'-propylenebis(piperazine-2,6-dione) Usage And Synthesis |
| Uses | Razoxane is an inhibitor of Topo II. | | Definition | ChEBI: Razoxane is a N-alkylpiperazine. | | Safety Profile | Suspected human carcinogen producing leukemia and skin tumors. Moderately toxic by intraperitoneal route. Human effects: normocytic anemia and thrombocytopenia. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. |
| | 4,4'-propylenebis(piperazine-2,6-dione) Preparation Products And Raw materials |
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