| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Clobenpropit dihydrobromide, VUF 9153
CAS:145231-45-4
Purity:>98% Package:10mg
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| | CLOBENPROPIT DIHYDROBROMIDE Basic information |
| Product Name: | CLOBENPROPIT DIHYDROBROMIDE | | Synonyms: | N-(4-Chlorobenzyl)-S-[3-(4(5)-imidazoyl)propyl]isothiourea dihydrobromide;3-(1H-Imidazol-4-yl)propyl ((4-chlorophenyl)methyl)carbamimidothioate;Carbamimidothioic acid, ((4-chlorophenyl)methyl)-, 3-(1H-imidazol-4-yl)propyl ester;S-(3-(4(5)-Imidazolyl))propyl-N-(4-chlorobenzyl)isothiourea;CarbaMiMidothioic acid, N-[(4-chlorophenyl)Methyl]-, 3-(1H-iMidazol-5-yl)propyl ester;[(4-Chlorophenyl)methyl]carbamimidothioic acid 3-(1H-imidazol-4-yl)propyl ester;([4-CHLOROPHENYL]METHYL)-3-(1H-IMIDAZOL-4-YL)PROPYL ESTER CARBAMIMIDOTHIOIC ACID DIHYDROBROMIDE;CLOBENPROPIT DIHYDROBROMIDE | | CAS: | 145231-45-4 | | MF: | C14H17ClN4S | | MW: | 308.83 | | EINECS: | 604-604-1 | | Product Categories: | Histamine receptor | | Mol File: | 145231-45-4.mol |  |
| | CLOBENPROPIT DIHYDROBROMIDE Chemical Properties |
| Boiling point | 525.3±60.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: >20 mg/mL | | form | solid | | pka | 14.55±0.10(Predicted) | | color | white |
| | CLOBENPROPIT DIHYDROBROMIDE Usage And Synthesis |
| Uses | Clobenpropit Dihydrobromide and it’s analogues functions as potent histamine H3 antagonist. | | Definition | ChEBI: An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA | | Biological Activity | An extremely potent histamine H 3 antagonist/inverse agonist (pA 2 =9.93). Also displays partial agonist activity at H 4 receptors; induces eosinophil shape change with an EC 50 of 3 nM. Also available as part of the Histamine H 3 Receptor Tocriset™ . | | Biochem/physiol Actions | Selective H3 histamine receptor antagonist that crosses the blood-brain barrier. |
| | CLOBENPROPIT DIHYDROBROMIDE Preparation Products And Raw materials |
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