| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Tel: |
029-81124267 15229202216 |
| Email: |
1073@dideu.com |
| Products Intro: |
Product Name:Desloratadine
Package:25kg
|
| Company Name: |
Jigs Chemical Limited
|
| Tel: |
+91 80 4290 2764 |
| Email: |
info@jigschemical.com |
| Products Intro: |
Product Name:Desloratadine
|
|
| | "Desloratadine Citrate Disodium" Basic information |
| | "Desloratadine Citrate Disodium" Chemical Properties |
| Melting point | 150-151°C | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Solid | | color | White to Beige |
| | "Desloratadine Citrate Disodium" Usage And Synthesis |
| Uses | Desloratadine (Loratadine EP Impurity D; Loratadine USP Related Compound A) is an active metabolite of Loratadine (L469575) and used as an oral non-sedating antihistamine to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria (1,2,3). | | Clinical Use | Antihistamine:
Symptomatic relief of allergy such as hay fever,
urticaria | | Drug interactions | Potentially hazardous interactions with other drugs
Antivirals: concentration possibly increased by
ritonavir. | | Metabolism | Desloratadine is the primary active metabolite of
loratadine. Approximately 40% of the dose is excreted
in the urine and 42% in the faeces over a 10 day period
and mainly in the form of conjugated metabolites.
Approximately 27% of the dose is eliminated in the urine
during the first 24 hours. Less than 1% of the active
substance is excreted unchanged in the active form, as
desloratadine. |
| | "Desloratadine Citrate Disodium" Preparation Products And Raw materials |
|