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Amiodarone hydrochloride

Amiodarone hydrochloride Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
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Products Intro: Product Name:Amiodarone hydrochloride
CAS:19774-82-4
Purity:99% Package:770/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
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Products Intro: Product Name:Amiodarone hydrochloride
CAS:199774-82-4
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Nanjing Gold Pharmaceutical Technology Co. Ltd.
Tel: 025-84209270 15906146951
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Products Intro: Product Name:Amiodarone hydrochloride
CAS:19774-82-4
Purity:99% Package:1000KG;;100KG;10KG;5KG;1KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
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Products Intro: CAS:199774-82-4
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
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Products Intro: Product Name:Amiodarone hydrochloride
CAS:19774-82-4
Amiodarone hydrochloride Basic information
Product Name:Amiodarone hydrochloride
Synonyms:Methanone,(2-butyl-3-benzofuranyl)[4-[2-(diethylaMino)ethoxy]-3,5-diiodophenyl]-,hydrochloride (1:1);AMiodarone hydrochloride API;AMidorone (HCl);Nexterone;AMiodarone iMpurity;(2-Butylbenzofuran-3-yl)(4-(2-(diethylaMino)ethoxy)-3,5-diiodophenyl)Methanone hydrochloride;2-BUTYL-3-BENZOFURANYL 4-[2-(DIETHYLAMINO)ETHOXY]-3,5-DIIODOPHENYL KETONE HYDROCHLORIDE;(2-BUTYL-3-BENZOFURANYL)-[4-[2-(DIETHYLAMINO)ETHOXY]-3,5-DIIODO-PHENYL]-METHANONE HYDROCHLORIDE
CAS:19774-82-4
MF:C25H29I2NO3.ClH
MW:681.77
EINECS:243-293-2
Product Categories:API;Active Pharmaceutical Ingredients;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API's;-;Ion transporter and other ion channel
Mol File:19774-82-4.mol
Amiodarone hydrochloride Structure
Amiodarone hydrochloride Chemical Properties
Melting point 154-158°C
Fp 9℃
storage temp. 2-8°C
solubility Soluble in chloroform, methanol.
pkapKa (25°C) 6.56 ±0.06
form neat
λmax242nm(MeOH)(lit.)
Merck 14,482
CAS DataBase Reference19774-82-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,T,F
Risk Statements 20/21/22-39/23/24/25-23/24/25-11
Safety Statements 36-45-36/37-16-7
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 3
RTECS OB1361000
HS Code 29322090
Hazardous Substances Data19774-82-4(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
Amiodarone hydrochloride Usage And Synthesis
Chemical PropertiesWhite Solid
UsesAntiarrhythmic;Na+ channel blocker
UsesA non-selective ion channel blocker. Antiarrhythmic (class III)
Enzyme inhibitorThis photosensitive benzofuran (FWfree-base = 645.32 g/mol; CAS 19774-82- 4 (HCl) ), also known as Nexterone and systematically as (2-{4-[ (2-butyl-1- benzofuran-3-yl) carbonyl]-2,6-diiodophenoxy}ethyl) diethylamine, is a non-selective ion channel blocker and an a- and b-adrenergic receptor agonist and antiarrhythmic agent used for various types of cardiac dysrhythmias, both ventricular and atrial. Key Pharmacokinetic Parameters: See Appendix II in Goodman & Gilman’s THE PHARMACOLOGICAL BASIS OF THERAPEUTICS, 12th Edition (Brunton, Chabner & Knollmann, eds.) McGraw-Hill Medical, New York. Target (s) : Na+ channels; phosphol2+ipase A1; calmodulin-dependent action ; protein kinase C ; Ca channels (6,1+0,1+6); carnitine palmitoyltransferase (I7); K+ channels; Na/K-exchanging ATPase; lysosomal phospholipases; phospholipase A2; phospholipase C; cholestenol D-isomerase, or sterol D7,8-isomerase; phosphatidylglycerol-selective phospholipase A2; retinyl ester hydrolase.
Amiodarone hydrochloride Preparation Products And Raw materials
Preparation ProductsAmiodarone
Tag:Amiodarone hydrochloride(19774-82-4) Related Product Information
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