K145 (hydrochloride) manufacturers
- K145 hydrochloride
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- $50.00 / 5mg
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2025-05-26
- CAS:1449240-68-9
- Min. Order:
- Purity: 99.09%
- Supply Ability: 10g
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| | K145 (hydrochloride) Basic information |
| Product Name: | K145 (hydrochloride) | | Synonyms: | K145 (hydrochloride);K145(HCl);3-(2-Aminoethyl)-5-[3-(4-butoxyphenyl)propylidene]-2,4-thiazolidinedione hydrochloride (1:1);3-(2-Amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione hydrochloride;K14 (hydrochloride);SphK2 inhibitor;SPHK2 INHIBITOR;K 145 HYDROCHLORIDE;K-145 HYDROCHLORIDE;K145 hydrochloride >=98% (HPLC) | | CAS: | 1449240-68-9 | | MF: | C18H25ClN2O3S | | MW: | 384.9207 | | EINECS: | | | Product Categories: | API | | Mol File: | 1449240-68-9.mol |  |
| | K145 (hydrochloride) Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: soluble20mg/mL, clear | | form | powder | | color | white to beige |
| | K145 (hydrochloride) Usage And Synthesis |
| Uses | K145 hydrochloride has been used in the analysis of apoptosis. | | General Description | K145 hydrochloride (3-(2-Amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione) is an analog of sphingosine. | | Biochem/physiol Actions | It has the ability to prevent leukemia cell growth in vitro. | | in vivo | K145 (50 mg/kg; oral gavage; daily; for 15 days; BALB/c-nu mice) treatment significantly inhibits the growth of U937 tumors in nude mice[1]. | Animal Model: | BALB/c-nu mice injected with U937 cells[1] | | Dosage: | 50 mg/kg | | Administration: | Oral gavage; daily; for 15 days | | Result: | Inhibited the growth of U937 tumors at 50 mg/kg dose and no apparent toxicity was observed.
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| | IC 50 | SphK2 |
| | K145 (hydrochloride) Preparation Products And Raw materials |
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