H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH

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H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH Basic information
Product Name:H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH
Synonyms:TYR-PHE-LEU-LEU-ARG-ASN-PRO;YFLLRNP;ALPHA-THROMBIN ANTAGONIST IN HUMAN PLATELETS;HUMAN ALPHA-THROMBIN;YFLLRNP, (Tyr1)-PAR-1 (1-7) (huMan), (Tyr1)-Proteinase Activated Receptor 1 (1-7) (huMan), (Tyr1)-ThroMbin Receptor (1-7) (huMan), (Tyr1)-ThroMbin Receptor Activator Peptide 7, (Tyr1)-Coagulation Factor II Receptor (1-7) (huMan);L-Tyrosyl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparaginyl-L-Proline;YFLLRNP trifluoroacetate;YFLLRNP-OH
CAS:149440-16-4
MF:C45H67N11O10
MW:922.08
EINECS:
Product Categories:
Mol File:149440-16-4.mol
H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH Structure
H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH Chemical Properties
density 1.38±0.1 g/cm3(Predicted)
storage temp. -15°C
solubility deionized water: soluble1mg/mL
form solid
pka3.37±0.20(Predicted)
Water Solubility deionized water: 1mg/mL
SequenceTyr-Phe-Leu-Leu-Arg-Asn-Pro
InChIKeyHMDRRCMAXMJXKF-WDYYMHPRSA-N
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH Usage And Synthesis
UsesYFLLRNP trifluoroacetate may be used as a powerful tool for differentiating the numerous possible activation states of the platelet thrombin receptor.
Biological ActivityYFLLRNP is a Galpha12/13-stimulating peptide th at activates the alpha granule secretion due to costimulation with either ADP or serotonin/epinephrine.', 'YFLLRNP is a PAR-1-specific partial agonist. The compound selectively activates the G(12/13) signaling cascade resulting in platelet shape.
H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH Preparation Products And Raw materials
Tag:H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH(149440-16-4) Related Product Information
Leupeptin Ac-LL Thrombin H-Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH RENIN Protein, HUMAN (HEK293, HIS) 2-(2-Furoyl)-Leu-Ile-Gly-Arg-Leu-Orn-NH2 I-191 (I191)