ChemicalBook > Product Catalog >Biochemical Engineering >Enzymes And Coenzymes drugs >Thrombin


Thrombin Suppliers list
Company Name: Shaanxi Dideu Medichem Co. Ltd
Products Intro: Product Name:Thrombin
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008615858145714
Products Intro: Product Name:Thrombin fandachem
Purity:As coa Package:As request Remarks:9002-04-4
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Products Intro: Product Name:Thrombin
Purity:40-300u/mg Package:1ku
Company Name: career henan chemical co
Tel: +86-371-86658258
Products Intro: Product Name:Thrombin
Purity:95%-99% Package:1kg;1USD
Company Name: Shandong chuangyingchemical Co., Ltd.
Tel: 18853181302
Products Intro: Product Name:Thrombin

Lastest Price from Thrombin manufacturers

  • Thrombin
  • US $0.00 / KG
  • 2021-09-29
  • CAS:9002-04-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20kg/month
  • Thrombin
  • US $0.00-0.00 / Kg
  • 2020-02-26
  • CAS: 9002-04-4
  • Min. Order: 1KG
  • Purity: 99.0%+
  • Supply Ability: 1000 tons
  • Thrombin
  • US $1.00 / kg
  • 2019-07-06
  • CAS:9002-04-4
  • Min. Order: 1kg
  • Purity: 95%-99%
  • Supply Ability: 1000kg

Related articles

  • The Way Things Work: Thrombin
  • Thrombin is the principal enzyme of hemostasis. It catalyzes the conversion of fibrinogen to fibrin and activates procoagulant....
  • Oct 30,2019
Thrombin Basic information
Product Name:Thrombin
Synonyms:Blood coagulation factor IIa;C00752;Thrombin from human plasma,Factor IIa;Thrombin from murine plasma,Factor IIa;Thrombin from bovine plasma,Factor IIa;THROMBIN, BOVINE;ThroMbin froM bovine plasMa 1000 units/Mg protein lyophil.;BOVINE THROMBIN
Product Categories:proteins
Mol File:Mol File
Thrombin Structure
Thrombin Chemical Properties
Melting point 47.7 °C
storage temp. -20°C
solubility H2O: 1 mL/vial clear to slightly hazy, colorless solution
form powder
color white
Merck 13,9461
EPA Substance Registry SystemThrombin (9002-04-4)
Safety Information
Hazard Codes Xn,B,Xi
Risk Statements 36/37/38-42
Safety Statements 22-24/25-36/37-26-24
WGK Germany 2
RTECS XO8950000
HS Code 30021099
MSDS Information
Thrombin English
SigmaAldrich English
Thrombin Usage And Synthesis
DescriptionIn order to stop local bleeding, thrombin, a natural thrombin drug that catalyzes the transformation of fibrinogen to fibrin, is frequently used. Thrombin is synthesized from cow plasma, and it is used to stop bleeding from open vessels when it is not possible to use other methods. It is used to stop light bleeding.
UsesThrombostat (Parke-Davis).
General DescriptionThrombin is a sterile protein substanceprepared from prothrombin of bovine origin. It is used as atopical hemostatic because it can clot blood, plasma, or a solutionof fibrinogen without addition of other substances.Thrombin also may initiate clotting when combined withgelatin sponge or fibrin foam.
For external use it is applied topically to the wound, as asolution containing 100 to 2,000 National Institutes ofHealth (NIH) units/mL in sodium chloride irrigation or sterilewater for injection or as a dry powder.
Purification MethodsThrombin is purified by chromatography on a DEAE-cellulose column, while eluting with 0.1M NaCl, pH 7.0, followed by chromatography on Sephadex G-200. The final preparation is free from plasminogen and plasmin. [Yin & Wessler J Biol Chem 243 112 1968.] Thrombin from bovine blood is also purified by chromatography using p-chlorobenzylamino--aminocaproyl agarose, and gel filtration through Sephadex G-25. [Thompson & Davie Biochim Biophys Acta 250 210 1971.] Thrombin from various species was purified initially by precipitation of impurities with rivanol. [Miller Nature 184 450 1959.] Tissue inhibitor of metalloproteins (TIMP, from human blood plasma), Mr ~30,000. These are purified by an [anti-human amniotic fluid-TIMP]-Sepharose immuno-affinity column and eluted with 50mM glycine/HCl pH 3.0 buffer that is 0.5M in NaCl, and followed by gel filtration [Cawston et al. Biochem J 238 677 1986].
Thrombin Preparation Products And Raw materials
Raw materialsTrisodium citrate dihydrate
Tag:Thrombin(9002-04-4) Related Product Information
Thrombin from Human, Recombinant Thrombin antibody Thrombin (F-1) Thrombin API (B-2) P Thrombin R (ATAP2) 2,4-PENTANEDIONE, SILVER DERIVATIVE COBALT(II) ACETYLACETONATE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Ethyl isocyanoacetate Cupric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) N-BUTYLISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) Tosylmethyl isocyanide COBALT ETHYLENE DIAMINE CHLORIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Aluminum acetylacetonate TERT-BUTYL ISOCYANIDE