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m-Cresol Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: Product Name:108-39-4
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 86-0551-65418684 18949823763
Products Intro: Product Name:M-Cresol;3-Methylphenol
Purity:99.5 Package:1ASSAYS;1USD
Company Name: career henan chemical co
Tel: +86-371-86658258
Products Intro: Product Name:m-Cresol
Purity:99% Package:1KG;1USD
Products Intro: Product Name:m-Cresol
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Products Intro: Product Name:m-cresol
Purity:99% Package:5KG;1KG

Lastest Price from m-Cresol manufacturers

  • m-Cresol
  • US $10.00 / KG
  • 2021-08-26
  • CAS:108-39-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 ton
  • m-Cresol
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:108-39-4
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • m-Cresol
  • US $15.00-10.00 / KG
  • 2021-07-10
  • CAS:108-39-4
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton

Related articles

  • m-Cresol- application
  • m-Cresol is a methylphenol compound, which is naturally occurring or synthetic, and can be used as cosmetic biocides/preservat....
  • Dec 17,2019
m-Cresol Basic information
Product Name:m-Cresol
Synonyms:m-Cresole;M-CRESOL;M-CRESOL 70;META-CRESOL;FEMA 3530;hydroxy-3-methylbenzene;M-CRESOL F & D VERSION;M-CRESOL APPROX 95%
Product Categories:alcohol;Phenoles and thiophenoles
Mol File:108-39-4.mol
m-Cresol Structure
m-Cresol Chemical Properties
Melting point 8-10 °C(lit.)
Boiling point 203 °C(lit.)
density 1.034 g/mL at 25 °C(lit.)
vapor density 3.72 (vs air)
vapor pressure <1 mm Hg ( 20 °C)
refractive index n20/D 1.541(lit.)
Fp 187 °F
storage temp. Store below +30°C.
solubility 23.5g/l
pka10.01(at 25℃)
form Liquid
color Clear colorless to slight red
PH5 (20g/l, H2O, 20℃)
explosive limit1.06-1.35%, 150°F
Odor Threshold0.0001ppm
Water Solubility 20 g/L (20 ºC)
Merck 14,2579
JECFA Number692
BRN 506719
Stability:Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, strong acids, aluminium, aluminium alloys. Air and light sensitive. Hygroscopic.
CAS DataBase Reference108-39-4(CAS DataBase Reference)
NIST Chemistry ReferencePhenol, 3-methyl-(108-39-4)
EPA Substance Registry Systemm-Cresol (108-39-4)
Safety Information
Hazard Codes T
Risk Statements 24/25-34-39/23/24/25-23/24/25
Safety Statements 36/37/39-45-36/37
RIDADR UN 2076 6.1/PG 2
WGK Germany 1
RTECS GO6125000
Autoignition Temperature626 °C
HazardClass 6.1
PackingGroup II
HS Code 29071200
Hazardous Substances Data108-39-4(Hazardous Substances Data)
ToxicityLD50 orally in rats: 2.02 g/kg (Deichmann, Witherup)
MSDS Information
m-Cresol English
SigmaAldrich English
ACROS English
ALFA English
m-Cresol Usage And Synthesis

m-Cresol is an important organic intermediate (building block) to synthetize substituted aryl products.

Chemical Propertiescolourless to light yellow liquid
Chemical PropertiesCresol is a mixture of the three isomeric cresols, o-, m-, and p-cresol. Cresols are slightly soluble in water. m-Isomer: Colorless or yellow liquid with characteristic odor.
Chemical Propertiesm-Cresol has a dry, tarry, medicinal–leathery odor. m-Cresol and p-cresol very often occur together and are difficult to separate.
OccurrenceReported found in beer, coffee, egg, grape, Oriental tobacco, roasted barley, rum, sherry and whiskey.
Usesm-Cresol is used as a disinfectant and solvent. LysolTM disinfectant is a 50% (v/v) mixed-cresol isomer in a soap emulsion formed on mixing with water. The isomer m-cresol is an oily liquid with low volatility. Besides disinfection at solutions of 1–5%, the cresols are used in degreasing compounds, paintbrush cleaners, and additives in lubricating oils. Cresols were once widely used for disinfection of poultry houses, but this use has been discontinued because they cause respiratory problems and abdominal edema in young chicks. m-Cresol has been used in synthetic resins, explosives, petroleum, photographic, paint, and agricultural industries.
UsesAntiseptic; antimicrobial preservative.
DefinitionChEBI: A cresol with the methyl substituent at position 3. It is a minor urinary metabolite of toluene.
PreparationOne process involving butylation and separation and followed by dealkylation produces m-cresol and ditertiary butyl p-cresol. From m, p-cresol (which is the main product of the recovery process) pure m-cresol can be obtained by extraction.
Production MethodsThe cresols (cresylic acids) are methyl phenols and generally appear as a mixture of isomers. m-Cresol is prepared from m-toluic acid or obtained from coal tar or petroleum (352, 355, 356). Crude cresol is obtained by distilling “gray phenic acid” at a temperature of ~180–201°C. The m-cresol may be separated from the crude or purified mixture by repeated fractional distillation in vacuo. It can also be prepared synthetically by diazotization of the specific toluidine or by fusion of the corresponding toluenesulfonic acid with sodium hydroxide.
Aroma threshold valuesAroma characteristics at 1.0%: phenolic, spicy eugenol-like, medicinal, smoky powdery with a leatherlike note.
Taste threshold valuesTaste characteristics at 2 ppm: phenolic, smoky, balsamic, medicinal and spicy eugenol-like
General DescriptionColorless liquid with a sweet tarry odor. Sinks and mixes slowly with water.
Air & Water ReactionsWater soluble.
Reactivity Profilem-Cresol is sensitive to air, light and heat. m-Cresol is also hygroscopic. m-Cresol can react vigorously with strong oxidizers and strong bases. m-Cresol reacts violently with nitric acid, oleum, chlorosulfonic acid, metals and strong acids. If the water content is below approximately 0.3% and the temperature above 248° F, the corrosion of aluminum and its alloys may occur violently. m-Cresol will attack some forms of plastics, coatings and rubber.
HazardQuestionable carcinogen.
Health HazardINHALATION: Mucosal irritation and systemic poisoning EYES: Intense irritation and pain, swelling of conjunctiva, and corneal damage may occur. SKIN: Intense burning, loss of feeling, wrinkling, white discoloration, and softening. Gangrene may occur. INGESTION: Burning sensation in mouth and esophagus. Vomiting may result. Acute exposure by all routes may cause muscular weakness, gastroenteric disturbances, severe depression, collapse. Effects are primarily on CNS and edema of lungs. Injury of spleen and pancreas may occur.
Contact allergensMetacresol is contained as a preservative in almost all human insulin. It has been reported as a cause of allergic reaction due to injected insulin.
Safety Profilev Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Moderately toxic by skin contact. Severe eye and skin irritant. An experimental teratogen. Human mutation data reported. Questionable carcinogen with experimental neoplastigenic data. Flammable when exposed to heat or flame. Moderately explosive in the form of vapor when exposed to heat or flame. See also other cresol entries and PHENOL.
Potential ExposureCresol is used as a disinfectant and fumigant; as an ore flotation agent, and as an intermediate in the manufacture of chemicals, dyes, plastics, and antioxidants. A mixture of isomers is generally used; the concentrations of the components are determined by the source of the cresol.
Carcinogenicitym-Cresol has induced a few papillomas but no carcinomas in tumor studies.
ShippingUN2076 Cresols, liquid, Hazard class: 6.1; Labels: 6.1-Poisonous materials, 8-Corrosive material. UN3455 Cresols, solid, Hazard class: 6.1; Labels: 6.1- Poisonous materials, 8-Corrosive material.
Purification MethodsSeparation of the m-and p-cresols requires chemical methods, such as conversion to their sulfonates [Brüchner Anal Chem 75 289 1928]. An equal volume of H2SO4 is added to m-cresol, stirred with a glass rod until solution is complete. Heat for 3hours at 103-105o. Dilute carefully with 1-1.5 volumes of water, heat to boiling point and steam distil until all unsulfonated cresol has been removed. Cool and extract the residue with ether. Evaporate the solution until the boiling point reaches 134o and steam distil off the m-cresol. Another purification method involves distillation, fractional crystallisation from the melt, then redistillation. Free from p-cresol by solution in glacial acetic acid and bromination by about half of an equivalent amount of bromine in glacial acetic acid. The acetic acid is distilled off, then fractional distillation of the residue under vacuum gives bromocresols from which 4-bromo-m-cresol is obtained by crystallisation from hexane. Addition of the bromocresol in glacial acetic acid slowly to a reaction mixture of HI and red phosphorus or (more smoothly) of HI and hypophosphorus acid, in glacial acetic acid, at reflux, removes the bromine. After an hour, the solution is distilled at atmospheric pressure until layers are formed. Then it is cooled and diluted with water. The cresol is extracted with ether, washed with water, NaHCO3 solution and again with water, dried with a little CaCl2 and distilled [Baltzly et al. J Am Chem Soc 77 2522 1955]. The 3,5-dinitrobenzoate (prepared with 3,5-dinitrobenzoyl chloride in dry pyridine, and recrystallised from EtOH or aqueous Me2CO) has m 165o. [Beilstein 6 IV 2035.]
IncompatibilitiesVapors may form explosive mixture with air. Incompatible with strong acids; oxidizers, alkalies, aliphatic amines; amides, chlorosulfonic acid; oleum. Decomposes on heating, producing strong acids and bases, causing fire and explosion hazard. Liquid attacks some plastics and rubber. Attacks many metals.
Waste DisposalWastewaters may be subjected to biological treatment. Concentrations may be further reduced by ozone treatment. High concentration wastes may be destroyed in special waste incinerators.
Tag:m-Cresol(108-39-4) Related Product Information
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