| Company Name: |
BOC Sciences
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16314854226 |
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info@bocsci.com |
| Products Intro: |
Product Name:Ethyl-L-NIO hydrochloride
CAS:150403-97-7
Purity:95% Package:1G;10G;100G
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| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:ETHYL-L-NIO (HYDROCHLORIDE)
CAS:150403-97-7
Purity:98% Package:10mg; 5mg; 100mg; 50mg Remarks:Medbio
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| Company Name: |
TCI (Shanghai) Chemical Trading Co., Ltd.
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021-61109150 |
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sales@tcisct.com |
| Products Intro: |
Product Name:chloro (2S)-2-amino-5-(1-aminobutylideneamino)pentanoate
CAS:150403-97-7
Package:1KG;10KG;100KG; Remarks: 纯度：根据客户需求提供
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| | ETHYL-L-NIO (HYDROCHLORIDE) Basic information |
| Product Name: | ETHYL-L-NIO (HYDROCHLORIDE) | | Synonyms: | ETHYL-L-NIO (HYDROCHLORIDE);L-N5-(1-IMINOBUTYL)ORNITHINE HYDROCHLORIDE;DWNWLIPSWIUXRG-FJXQXJEOSA-N;chloro (2S)-2-amino-5-(1-aminobutylideneamino)pentanoate;EthylLNIO (hydrochloride),Ethyl L NIO (hydrochloride);L-Ornithine, N5-(1-iminobutyl)-, monohydrochloride (9CI) | | CAS: | 150403-97-7 | | MF: | C9H18ClN3O2 | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 150403-97-7.mol |  |
| | ETHYL-L-NIO (HYDROCHLORIDE) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 0.3 mg/ml; DMSO: 2 mg/ml; Ethanol: 2.5 mg/ml; PBS (pH 7.2): 5 mg/ml | | form | A crystalline solid |
| | ETHYL-L-NIO (HYDROCHLORIDE) Usage And Synthesis |
| Description | Ethyl-L-NIO, the saturated analog of vinyl-L-NIO, is a modestly selective NOS inhibitor. The Ki values for inhibition of nNOS, eNOS, and iNOS by ethyl-L-NIO are 5.3, 18, and 12 μM, respectively, as determined using initial rate measurements. However when evaluating the Ki/Km ratio, ethyl-L-NIO does not show biologically significant selectivity for nNOS over eNOS, and instead favors iNOS (Ki/Km = 3.79, 5, and 0.96 μM, respectively). Although ethyl-L-NIO inhibits nNOS, it does not inactivate nNOS in the presence of NADPH and O2. |
| | ETHYL-L-NIO (HYDROCHLORIDE) Preparation Products And Raw materials |
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