| Company Name: |
CLEARSYNTH LABS LTD.
|
| Tel: |
+91-22-45045900 |
| Email: |
sales@clearsynth.com |
| Products Intro: |
Product Name:Thenalidine
CAS:86-12-4
|
| Company Name: |
United States Biological
|
| Tel: |
800.520.3011 or 781.639.5092 |
| Email: |
chemicals@usbio.net |
| Products Intro: |
Product Name:Thenalidine
CAS:86-12-4
|
- thenalidine USP/EP/BP
-
- $1.10 / 1g
-
2021-06-17
- CAS:86-12-4
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
|
| | thenalidine Basic information |
| Product Name: | thenalidine | | Synonyms: | thenalidine;1-Methyl-4-[phenyl(2-thienylmethyl)amino]piperidine;Sandostene;Thenalidin;Thenophenopiperidine;Thenaldine;4-Piperidinamine, 1-methyl-N-phenyl-N-(2-thienylmethyl)-;thenalidine USP/EP/BP | | CAS: | 86-12-4 | | MF: | C17H22N2S | | MW: | 286.43 | | EINECS: | 201-651-5 | | Product Categories: | | | Mol File: | 86-12-4.mol |  |
| | thenalidine Chemical Properties |
| Melting point | 95-97° | | Boiling point | bp0.02 158-160° | | density | 1.140±0.06 g/cm3(Predicted) | | pka | pKa 3.36±0.06(H2O
t undefined
I = 0.30
(NaCl)) (Uncertain);8.39±0.07(H2O
t undefined
I = 0.30
(NaCl)) (Uncertain) |
| | thenalidine Usage And Synthesis |
| Uses | Thenalidine is an antihistamine that has anticholinergic properties which is used as an antipruritic drugs. | | Definition | ChEBI: Thenalidine is a dialkylarylamine and a tertiary amino compound. | | Brand name | Sanbosten. | | World Health Organization (WHO) | Thenalidine, a piperidine antihistamine, was introduced in 1953
for the management of dermatologic and allergic conditions. By 1958 its use had
been associated with cases of severe neutropenia, two of them fatal, which led to
its withdrawal in the United States of America and subsequently in the United
Kingdom. Over the next fifteen years, continued reports of its association with
cases of neutropenia resulted in further withdrawals in many countries. It is
apparently still available, however, in some combination products. | | Synthesis | Thenalidine is synthesized by
alkylation of 1-methyl-4-phenylaminopiperidine
with 2-chloromethyl thiophene . |
| | thenalidine Preparation Products And Raw materials |
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