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Sodium levothyroxine

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Sodium levothyroxine Basic information
Uses
Product Name:Sodium levothyroxine
Synonyms:SODIUM LEVOTHYROXINE;SODIUM LEVOTHYROXINE, HYDRATE;sodium (2s)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate;3-[4-4-HYDROXY-3,5-DIIODOPHENOXY-3,5-DIIODOPHENYL]-L-ALANINE, HYDRATE;L-THYROXINE SODIUM SALT;L-THYROXINE SODIUM SALT, HYDRATE;L-THYROXINE SODIUM, HYDRATE;L-THYROXIN SODIUM
CAS:25416-65-3
MF:C15H10I4NNaO4
MW:798.85
EINECS:685-634-1
Product Categories:Hormone Drugs;25416-65-3
Mol File:25416-65-3.mol
Sodium levothyroxine Structure
Sodium levothyroxine Chemical Properties
Melting point 207 °C
alpha 16 º (c=2,1M HCl/alcohol 1/4)
storage temp. Inert atmosphere,2-8°C
solubility Very slightly soluble in water, slightly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides.
form Liquid
color Clear yellow to yellow-greenish
Water Solubility 0.15 g/L (25 ºC)
Stability:Hygroscopic
Major Applicationagriculture
environmental
InChIInChI=1/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/s3
InChIKeyYDTFRJLNMPSCFM-ZLBVLXFENA-M
SMILESC1(=CC(=C(O)C(I)=C1)I)OC1=C(I)C=C(C[C@H](N)C([O-])=O)C=C1I.[Na+] |&1:16,r|
CAS DataBase Reference25416-65-3(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29379000
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsSTOT RE 1
MSDS Information
Sodium levothyroxine Usage And Synthesis
UsesL-Thyroxine sodium hydrate is a useful research chemical. Its free form Thyroxine (T425600) is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
Chemical Propertiesalmost white to beige or
UsesThyroid hormone replacement.
DefinitionChEBI: Levothyroxine sodium hydrate is an organic molecular entity.
Brand nameLevo-T (Alara); Levolet (Vintage); Levothroid (Lloyd); Levoxyl (Jones); Novothyrox (Genpharm); Synthroid (Abbott); Unithroid (Stevens J).
Sodium levothyroxine Preparation Products And Raw materials
Preparation ProductsLevothyroxine sodium
Tag:Sodium levothyroxine(25416-65-3) Related Product Information
Sodium acetate Sodium chloride Sodium bicarbonate Sodium hydroxide TSH 4-Methoxyphenylacetone Sodium formate Sodium carbonate Phenylhydrazine Sodium gluconate Sodium propionate Diphenylsilanediol Diclofenac sodium Sodium benzoate 3,3',5-Triiodo-L-thyronine Levothyroxine Chlorophosphonazo III Phenyl valerate