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Carbonic Anhydrase IX/XII Inhibitor II(U-104)

Carbonic Anhydrase IX/XII Inhibitor II(U-104) Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: Product Name:U-104
CAS:178606-66-1
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: career henan chemical co
Tel: +86-0371-55982848
Email: sales@coreychem.com
Products Intro: Product Name:Carbonic Anhydrase IX/XII Inhibitor II(U-104)
CAS:178606-66-1
Purity:98% Package:1KG;1USD
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Email: linda@hubeijusheng.com
Products Intro: Product Name:Carbonic Anhydrase IX/XII Inhibitor II(U-104)
CAS:178606-66-1
Purity:0.99 Package:5KG;1KG
Company Name: BOC Sciences
Tel: 1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:SLC-0111
CAS:178606-66-1
Package:$178/50mg Remarks:SLC-0111, also known as U-104, MST-104 and NSC 213841, is a potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Email: sales@alchempharmtech.com
Products Intro: CAS:178606-66-1
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-72770

Carbonic Anhydrase IX/XII Inhibitor II(U-104) manufacturers

  • U-104
  • $0.00-0.00 / KG
  • 2021-07-20
  • CAS:178606-66-1
  • Min. Order: 5mg
  • Purity: 99%
  • Supply Ability: 2000tons
Carbonic Anhydrase IX/XII Inhibitor II(U-104) Basic information
Product Name:Carbonic Anhydrase IX/XII Inhibitor II(U-104)
Synonyms:NSC 213841;Carbonic Anhydrase IX/XII Inhibitor II(U-104);U-104;MST-104 ;4-[[[(4-Fluorophenyl)amino]carbonyl]amino]benzenesulfonamide;CS-1653;arbonic Anhydrase IX/XII Inhibitor II(U-104);NSC-213841; MST-104;U104;U 104
CAS:178606-66-1
MF:C13H12FN3O3S
MW:309.32
EINECS:
Product Categories:Inhibitors;Inhibitor
Mol File:178606-66-1.mol
Carbonic Anhydrase IX/XII Inhibitor II(U-104) Structure
Carbonic Anhydrase IX/XII Inhibitor II(U-104) Chemical Properties
Melting point 242-243℃
density 1.523±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C
solubility DMSO: >15mg/mL
form powder
pka9.94±0.12(Predicted)
color white to beige
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
WGK Germany 3
MSDS Information
Carbonic Anhydrase IX/XII Inhibitor II(U-104) Usage And Synthesis
UsesU 104 targets hypoxia-induced carbonic anhydrase IX, which inhibits tumor growth and metastasis.
Biochem/physiol ActionsU-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growth and metastasis formation in both spontaneous and experimental models of metastasis. U-104 reduces the medium acidity by inhibiting the catalytic activity of the CA IX. It binds specifically only to hypoxic cells expressing CA IX.
Carbonic Anhydrase IX/XII Inhibitor II(U-104) Preparation Products And Raw materials
Raw materials4-Fluorophenyl isocyanate-->Sulfanilamide
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