- acrisorcin USP/EP/BP
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- $1.10 / 1g
-
2021-07-20
- CAS:7527-91-5
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- acrisorcin
-
- $0.01 / 1KG
-
2020-05-13
- CAS:7527-91-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50 tons
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| | acrisorcin Basic information |
| Product Name: | acrisorcin | | Synonyms: | acrisorcin;acridin-9-amine,4-hexylbenzene-1,3-diol;acrisorcin USP/EP/BP;Acrisorcina;Akrinol;Bis(9-aminoacridinium)salz des hexylresorcine | | CAS: | 7527-91-5 | | MF: | C13H10N2.C12H18O2 | | MW: | 388.508 | | EINECS: | 2313897 | | Product Categories: | | | Mol File: | 7527-91-5.mol |  |
| | acrisorcin Chemical Properties |
| | acrisorcin Usage And Synthesis |
| Originator | Aminacrine
hexylresorcinate
,ZYF Pharm | | Uses | Antifungal. | | Manufacturing Process | 4-Hexylresorcinol 194.0 g is added to a solution composed of 56.1 g
potassium hydroxide in 1.5 L of water with stirring, and the mixture heated to
about 40°C to effect complete solution. The pH of this solution is 12. A second
solution of 9-aminoacridine hydrochloride is prepared as follows: 2 L of water
containing 83 ml of concentrated hydrochloric acid are heated with stirring to
about 80°C. Slowly 194.0 g of 9-aminoacridine are added. Heating is
continued until a clear solution is obtained. About 2 ml of additional
concentrated hydrochloric acid are added in small increments until the solution
is slightly acid (pH of about 6). The 4-hexyl resorcinol solution is now slowly
added under rapid agitation to the 9-aminoacridine hydrochloride solution. A
copious precipitate is formed which, upon :stirring and continued addition of
the 4-hexylresorcinol solution, becomes a creamy yellow slurry. At the end of
the addition, the pH is 7-8 (indicator paper). The slurry is stirred while heated
for an additional 15 min and then rapidly filtered on a 15 cm Buchner funnel.
The product thus obtained is washed thoroughly, using about 1 L of cold
water, to give a very pale yellow color in the last wash. The compound is then
pressed dry and then oven-dried for 2-3 h at 50°C. The resultant product, 9-
aminoacridine 4-hexyl resorcinolate, has a melting point of 189°-190°C. | | Brand name | Akrinol (Schering). | | Therapeutic Function | Antifungal, Anthelmintic |
| | acrisorcin Preparation Products And Raw materials |
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