Product Details
| Product Name: Raloxifene hydrochloride | CAS No.: 82640-04-8 |
| EC-No.: 639-789-7 | Min. Order: 1g |
| Purity: 99% | Supply Ability: 5000kg |
| Release date: 2021/12/23 |
Product Name: Raloxifene hydrochloride
CAS: 82640-04-8
MF: C28H28ClNO4S
MW: 510.04
EINECS: 639-789-7
Melting point 250-253°C
storage temp. -20°C Freezer
solubility DMSO: 28 mg/mL, soluble
form solid
color light yellow
λmax 286nm(lit.)
Raloxifene It is noteworthy that this molecule was formerly under development as keoxifene for breast cancer and prostatic hypertrophy. Raloxifene can be prepared by acylation of 6-methoxy-2-(4-methoxyphenyl) benzothiophene followed by simultaneous demethylation of both methoxy groups. Raloxifen is a selective estrogen receptor modulator, exerting antiestrogenic action on certain tissues (breast) and also estrogenic action on bone metabolism or serum lipids. In normal early postmenopausal women, 200 mg daily produced a trend towards suppression of estrogen effects. Raloxifen impeded bone loss in osteoporosis. A two-year study in postmenopausal women with an increased risk for osteoporosis showed that Raloxifen markedly prevented non-traumatic vertebral fractures. Results of several clinical studies demonstrated that Raloxifen appreciably reduced the risk of developing breast cancer. Moreover, it had favourable effect on lipid profiles without having the potential side-effects of estrogen-based therapies. Several extensions for different uses of this molecule are planned, for example growth disorder, obesity, colon tumor and skin atrophy. No serious drug-related events have been reported in the limited number of clinical trials.
Company Profile Introduction
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD is located in Jiangxia District, Wuhan City, Hubei Province. Main pharmaceutical intermediates, raw materials, food additives, antibiotics raw materials, etc. Wuhan dongkangyuan Technology Co., Ltd. is located in Wuhan, the thoroughfare of nine provinces. It is a high-tech industrial company specializing in the R & D and sales of chemical raw materials in Central China. The company has its own R & D base, equipped with advanced production equipment and high-efficiency precision testing instruments, with a complete, scientific and quality management system. And constantly committed to technological innovation, product innovation and management innovation, with high-tech and excellent innovation quality service has won the trust of University organs, scientific research institutions, pharmaceutical manufacturers, quality inspection departments, environmental protection enterprises, chemical production, agricultural production, food related industries and other industries. In order to ensure that our products in the same industry with super competitiveness. The company has independent import and export operation rights and excellent sales team.
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China- Since: 2013-04-05
- Address: Yuanfen Road community, Wuchang District, Wuhan City
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