Letrozole
Price | $850 |
Package | 1Kg |
Min. Order: | 1g |
Supply Ability: | 5000kg |
Update Time: | 2021-12-23 |
Product Details
Product Name: Letrozole | CAS No.: 112809-51-5 |
EC-No.: 675-034-8 | Min. Order: 1g |
Purity: 99% | Supply Ability: 5000kg |
Release date: 2021/12/23 |
Product Name: Letrozole
CAS: 112809-51-5
MF: C17H11N5
MW: 285.30274
EINECS: 675-034-8
Melting point 181-183°C
Boiling point 563.5±60.0 °C(Predicted)
density 1.21±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO: >50mg/mL
form White powder
pka 1.52±0.11(Predicted)
color white to off-white
Letrozole is part of a new generation of highly selective aromatase inhibitors and is an artificially synthesized benzotriazole derivative. Letrozole inhibits aromatase to lower estrogen levels, thus preventing estrogen from stimulating tumor growth. Its in vivo activity is 150-250 times stronger than that of first generation aromatase inhibitor Amarante. As it is highly selective, it will not impact glucocorticoid, mineralocorticoid and thyroid functions; even at high dosages, it will not have any inhibiting effects on adrenal corticosteroid secretion, giving it a high treatment index. Letrozole has no latent toxicity towards any bodily systems and target organs, has no mutagenicity and carcinogenic effects, has minimal toxic side effects, is well-tolerated, and has stronger anticancer effects than other aromatase inhibitors and antiestrogen drugs. Letrozole is suitable for advanced breast cancer postmenopausal patients who have not responded to estrogen-suppressing treatment and for early breast cancer treatment. It is used to treat postmenopausal patients with advanced breast cancer and serves as a second-line treatment to follow unsuccessful antiestrogen treatment. Compared to the current standard Tamoxifen treatment, Letrozole can better prevent the risk of breast cancer recurrence.
Company Profile Introduction
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD is located in Jiangxia District, Wuhan City, Hubei Province. Main pharmaceutical intermediates, raw materials, food additives, antibiotics raw materials, etc. Wuhan dongkangyuan Technology Co., Ltd. is located in Wuhan, the thoroughfare of nine provinces. It is a high-tech industrial company specializing in the R & D and sales of chemical raw materials in Central China. The company has its own R & D base, equipped with advanced production equipment and high-efficiency precision testing instruments, with a complete, scientific and quality management system. And constantly committed to technological innovation, product innovation and management innovation, with high-tech and excellent innovation quality service has won the trust of University organs, scientific research institutions, pharmaceutical manufacturers, quality inspection departments, environmental protection enterprises, chemical production, agricultural production, food related industries and other industries. In order to ensure that our products in the same industry with super competitiveness. The company has independent import and export operation rights and excellent sales team.
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- Since: 2013-04-05
- Address: Yuanfen Road community, Wuchang District, Wuhan City
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