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Postion:Product Catalog >API>Hormones and the Endocrine System>Pancreatic hormone and blood sugar regulation>Gliclazide
Gliclazide
  • Gliclazide
  • Gliclazide
  • Gliclazide
  • Gliclazide
  • Gliclazide

Gliclazide NEW

Price $125 $85 $65
Package 1Kg/Bag 25Kg/Bag 100Kg/Bag
Min. Order: 1Kg/Bag
Supply Ability: 20 tons
Update Time: 2024-04-22

Product Details

Product Name: Gliclazide CAS No.: 21187-98-4
EC-No.: 244-260-5 Min. Order: 1Kg/Bag
Purity: BP2017 Supply Ability: 20 tons
Release date: 2024/04/22

Product Information

Product name

Gliclazide

CAS No.

21187-98-4

Molecular Formula

C15H21N3O3S

Molecular Weight

323.4105

Quality Standard

99% up by HPLC, Medical Grade

Appearance

White powder



Usage

Function of Gliclazide

Gliclazide is a second-generation sulfonylurea hypoglycemic drug, which is a secretion promoter. Its hypoglycemic mechanism is to selectively act on the β cells of the pancreatic islets to promote the secretion of insulin and increase the secretion of insulin after eating, so that the liver Glycogen production and output are inhibited, which is helpful for the prevention and treatment of diabetic microvascular disease. Gliclazide has a long and stable action time, and is generally used in elderly patients. Gliclazide is generally absorbed quickly after oral administration, reaching a peak in 3-4 hours, and 80% is excreted from the kidneys. If the kidney function is not good, attention should be paid. Less common side effects are gastrointestinal reactions, such as nausea and vomiting, and the incidence of hypoglycemia is less than that of other sulfonylureas. Gliclazide can be used alone or simultaneously with other hypoglycemic drugs. Its hypoglycemic level is practical and reliable, and it can be combined with biguanides, insulin sensitizers, DPP-4 inhibitors and insulin, and different combinations can be made according to different conditions of patients.


COA of Gliclazide


Item

Specification

Test Result

Characteristics

White or almost white powder

White powder

Solubility

Practically insoluble in water:

freely soluble in methylene chloride;

Sparingly soluble in acetone(96%); slightly soluble in alcohol (96%)

Conforms

M.P

162-166°C

164.0-164.5° C

Identification

Conform to the spectrum of the CRS Gliclazide

Conforms

Heavy metals

≤10ppm

<10ppm

Impurity B

≤2ppm

0.3ppm

Related substances

Impurity F ≤0.10%

<0.10%

Other single impurity ≤0.10%

<0.10%

Total of other impurities ≤0.2%

<0.13%

Loss on drying

≤0.25%

0.10%

Sulphated ash

≤0.1%

0.01%

Residual solvents

Ethyl acetate ≤0.5%

Below LOQ

Toluene ≤0.089%

Below LOQ

Assay (on dried basis)

99.0%-101.0%

99.5%

Conclusion

The Results Conforms With Enterprise Standards

Article illustration

Article illustration

Article illustration





Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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